Results 121 to 130 of about 26,322 (251)

Metformin as a Multifaceted Therapeutic Agent for Gastrointestinal Diseases: Mechanisms, Clinical Efficacy, and Future Directions

Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
ABSTRACT The high prevalence of gastrointestinal (GI) diseases and their significant impact on the quality of life require new therapeutic strategies. The development of novel therapeutic strategies should prioritize targeting the fundamental pathophysiological mechanisms underlying these diseases, including inflammation, cellular proliferation, and ...
Sayedeh Azimeh Hosseini, Hassan Valadbeigi, Seyedeh Mahdieh Khoshnazar, Saeed Khoshnood, Shahab Falahi, Delsuz Rezaee, Ali Hematian, Mohammad Hossein Haddadi   +7 more
wiley   +1 more source

Advancing proton therapy: Dosimetric superiority of proton arc therapy over IMPT in esophageal cancer treatment

Journal of Applied Clinical Medical Physics, Volume 27, Issue 5, May 2026.
Abstract Background and aims Esophageal cancer presents significant treatment challenges due to its proximity to critical structures such as the heart, lungs, and spinal cord. While intensity‐modulated proton therapy (IMPT) improves dose conformity, it is limited by factors such as the number of beam angles and lateral penumbra. Proton arc therapy (PAT)
Xiaoda Cong, Ebin Sebastian, Peilin Liu, Xiaoqiang Li, James Dolan, Raymond Dalfson, Martin Soukup, Etienne Lessard, Rohan L. Deraniyagala, Craig W. Stevens, Peter Y. Chen, Xuanfeng Ding   +11 more
wiley   +1 more source

The Prevalence of Esophageal Hypomotility and Its Relationship With Dysmotility Score in Vietnamese Patients Having Reflux Symptoms

JGH Open
Aim This study aimed to determine the prevalence of esophageal hypomotility and examine its association with FSSG scores among Vietnamese patients presenting with reflux symptoms.
Hung Hoang Manh, Hue Luu Thi Minh, Trang Nguyen Thi Huyen, Phuong Do Nhat, Long Hoang Bao, Long Dao Van, Hang Dao Viet   +6 more
doaj   +1 more source

Complicated Benign Peptic Stricture of the Esophagus [PDF]

, 2010
Peptic esophageal stricture secondary to gastroesophageal reflux is an important cause of esophageal stenosis and dysphagia. Symptoms of peptic strictures are usually insidious but progressive beginning with dysphagia to solids followed by dysphagia to ...
Abdullah, M. (Murdani), Mulia, M. (Mulia), Simadibrata, M. (Marcellus), Tenggara, J. B. (Jeffry)   +3 more
core  

Immune Checkpoint Inhibitors and Immunomodulators for Cancer Immunotherapy: Insights Into Resistance and Therapeutic Strategies

Advanced Science, Volume 13, Issue 25, 4 May 2026.
The schematic diagram illustrates the roles of novel immune checkpoints, immunomodulatory factors, cell death and multimodal technologies in cancer immunotherapy. Abstract Cancer immunotherapy has redefined cancer treatment. However, the molecular and cellular basis of immune evasion and therapeutic resistance remains incompletely understood.
Fangquan Chen, Yang Yu, Xiutao Cai, Junhao Lin, Ruirui Liang, Rui Kang, Daolin Tang, Jiao Liu   +7 more
wiley   +1 more source

Maternal Fish Intake in the Year Prior to Conception and Birth Defects, National Birth Defects Prevention Study, 1997–2011

Birth Defects Research, Volume 118, Issue 5, May 2026.
ABSTRACT Background Epidemiologic data on the association between maternal fish intake and birth defects are sparse. Our objective was to assess associations between maternal fish intake and 52 different birth defects, most of which have not been assessed previously.
Dorothy Kim Waller, Zeyu Miao, Renata H. Benjamin, Richard Finnell, Nithya Lakshmi Mohan Dass, Eirini Nestoridi, Marcia C. de Oliveira Otto, Julie Peterson, Tunu Ramadhani, Mark A. Canfield, the National Birth Defects Prevention Study   +10 more
wiley   +1 more source

Chronic cough is associated with long breaks in esophageal peristaltic integrity on high-resolution manometry [PDF]

, 2018
Bennett, Michael C., Gyawali, C Prakash, Patel, Amit, Sainani, Nitin, Sayuk, Gregory S, Wang, Dan   +5 more
core   +2 more sources

Radiographic and ultrasonographic evaluation of the esophagus in the horse [PDF]

, 2016
The purpose of this study was to describe the radiographic and ultrasonographic appearance of the esophagus of ten healthy horses. Contrast radiography showed variations in the long-axis shape of the esophagus at the thoracic inlet.
Palmers, K, Pardon, Bart, Paulussen, Ellen, Picavet, MT, Van der Vekens, Elke, van Loon, Gunther   +5 more
core  

A Core Head, Neck, and Neuroanatomy Syllabus for Physical Therapy Student Education

Clinical Anatomy, Volume 39, Issue 4, Page 436-460, May 2026.
ABSTRACT Head, neck, and neuroanatomy are essential components of physical therapy education due to their broad clinical applications. Detailed syllabi exist for medical students, yet none have been developed for physical therapy. This study aimed to produce an International Federation of Associations of Anatomists core head, neck, and neuroanatomy ...
Stephanie J. Woodley, Brooke Willoughby, Alexandra L. Webb, Natasha A. M. S. Flack, Laura Y. Whitburn   +4 more
wiley   +1 more source

Ca2+/calmodulin/MLCK pathway initiates, and RhoA/ROCK maintains, the internal anal sphincter smooth muscle tone. [PDF]

, 2016
Rattan, Satish
core   +2 more sources