Results 211 to 220 of about 561,228 (312)

Hospital variation in treatment for synchronous metastatic esophageal and gastric cancer: A nationwide population‐based study in the Netherlands

open access: yesInternational Journal of Cancer, EarlyView.
What's New? A range of treatment options exist for metastatic esophageal (EC) and gastric cancer (GC). Which modalities or combination thereof are optimal for these malignancies, however, remains uncertain. Here, the authors examined differences in systemic treatment for metastatic EC and GC across hospitals in the Netherlands.
Julie F. M. Geerts   +11 more
wiley   +1 more source

A promising frontier of circulating messenger RNA in liquid biopsy: From mechanisms to clinical applications

open access: yesInternational Journal of Cancer, EarlyView.
Abstract Liquid biopsy can revolutionize cancer patient management as repeated sampling allows real‐time monitoring of disease progression and response to treatment. The circulating transcriptome represents a rich source of potential cancer biomarkers, including coding and non‐coding RNAs.
Mengqian Li   +7 more
wiley   +1 more source

Real‐world study on fluoropyrimidine‐related toxicity outcomes in cancer patients with select DPYD variant alleles that received DPYD genotype‐guided dosing

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Fluoropyrimidines, a key component of chemotherapy regimens for a variety of solid tumors, can cause severe toxicity. Patients who have specific genetic variants in the DPYD gene, which encodes an enzyme that inactivates fluoropyrimidines, have increased susceptibility to this toxicity.
Sofía L. J. Peeters   +12 more
wiley   +1 more source

Sizing and concentration analysis of cfDNA using Biabooster technology: Results from a prospective plasma‐based collection of 77 patients with locally advanced unresectable esophageal cancer

open access: yesInternational Journal of Cancer, EarlyView.
What's New? This study introduces a novel approach for detecting locally advanced esophageal carcinoma using cell‐free DNA (cfDNA) analysis through a highly sensitive fragmentome assay. Unlike traditional sequencing‐based methods that are limited by the absence of specific mutations in esophageal tumors, our method offers an alternative by quantifying ...
Anouchka Modesto   +21 more
wiley   +1 more source

Diagnosis and surgical management of a rare esophageal GIST: A case report and review of literature. [PDF]

open access: yesInt J Surg Case Rep
Zaiem A   +5 more
europepmc   +1 more source

The role of UPR‐related long noncoding RNAs in development of endocrine resistance in breast cancer

open access: yesInternational Journal of Cancer, EarlyView.
Abstract Breast cancer patients who express estrogen receptor α (ER) typically receive endocrine therapy as a first‐line treatment. Most ER‐positive breast cancer patients initially respond to endocrine therapy, but up to 40% of patients develop resistance over time, and the main mechanism is aberrant activation of ER signaling pathways.
Wen Liu, Sahil Gupta, Sanjeev Gupta
wiley   +1 more source

The incidence of esophageal second primary cancer in head and neck cancer patients. [PDF]

open access: yesMedicine (Baltimore)
Chiou TW   +6 more
europepmc   +1 more source

A Case of Malignant Melanoma Metastasis in the Ileal Conduit

open access: yesIJU Case Reports, EarlyView.
ABSTRACT Introduction Tumor development in the ileal conduit is rare. Herein, we present a case of metastatic malignant melanoma occurring within the ileal conduit 17 years after radical cystectomy. Case Presentation A 76‐year‐old Japanese man, with a history of bladder cancer treated with radical cystectomy and ileal conduit diversion, presented with ...
Noritoshi Shamoto   +9 more
wiley   +1 more source

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