Gene and protein expression of glucose transporter 1 and glucose transporter 3 in human laryngeal cancer—the relationship with regulatory hypoxia-inducible factor-1α expression, tumor invasiveness, and patient prognosis [PDF]
, 2014 Increased glucose uptake mediated by glucose transporters and reliance on glycolysis are common features of malignant cells. Hypoxia-inducible factor-1α supports the adaptation of hypoxic cells by inducing genes related to glucose metabolism.
Anna Krześlak +51 more
core +1 more source
Prospective, open, multi-centre phase I/II trial to assess safety and efficacy of neoadjuvant radiochemotherapy with docetaxel and oxaliplatin in patients with adenocarcinoma of the oesophagogastric junction [PDF]
, 2013 Background: This phase I/II-trial assessed the dose-limiting toxicities (DLT) and maximum tolerated dose (MTD) of neoadjuvant radiochemotherapy (RCT) with docetaxel and oxaliplatin in patients with locally advanced adenocarcinoma of the oesophagogastric ...
Arnold, Dirk +12 more
core +1 more source
Endoscopic Screening for Second Primary Tumors of the Esophagus Among Head and Neck Cancer Patients
Frontiers in Oncology, 2022 Malignancies of the head and neck (HN) region and esophagus are among the most common cancers worldwide. Due to exposure to common carcinogens and the theory of field cancerization, HN cancer patients have a high risk of developing second primary tumors (
Chen-Shuan Chung +23 more
doaj +1 more source
EZH2 Single Nucleotide Variants (SNVs): Diagnostic and Prognostic Role in 10 Solid Tumor Types [PDF]
, 2017 The enhancer of zeste homolog 2 (EZH2) gene encodes a histone methyltransferase that is a catalytic subunit of the Polycomb repressive complex 2 (PRC2) group of proteins that act to repress gene expression.
Crea, Francesco +4 more
core +2 more sources
Advanced Esophageal Neoplasm with Subcutaneous Metastasis [PDF]
Case Reports in Oncological Medicine, 2019 Objective. This report is aimed at describing a rare clinical condition of advanced esophageal cancer with subcutaneous metastasis. Case Report. The present case refers to a patient diagnosed with stage IV esophageal squamous cell carcinoma which started with dysphonia and cervical nodules.
Rivadávio A. M. de Oliveira +5 more
openaire +3 more sources
Non-coding RNAs in saliva: emerging biomarkers for molecular diagnostics. [PDF]
, 2015 Saliva is a complex body fluid that comprises secretions from the major and minor salivary glands, which are extensively supplied by blood. Therefore, molecules such as proteins, DNA, RNA, etc., present in plasma could be also present in saliva.
Majem, Blanca +3 more
core +4 more sources
Synchronous advanced gastric adenocarcinoma and advanced esophageal squamous cell carcinoma [PDF]
, 2002 CONTEXT: Synchronous associations of esophageal and gastric cancers are not a common finding, especially with differing histological types and both tumors in advanced forms.
Del Grande, José Carlos +4 more
core +3 more sources
Self Dilation of Esophageal Strictures
Canadian Journal of Gastroenterology, 1991 Over 22 years, 26 patients were taught to dilate their esophageal strictures. Fifteen had peptic strictures, four malignant neoplasms, three achalasia, three dysphagia following fundoplication and one esophageal lichen planus.
Stephen N Sullivan +2 more
doaj +1 more source
Российский журнал гастроэнтерологии, гепатологии, колопроктологии, 2019 Aim. The present guidelines intended for primary care physicians are aimed at facilitating early diagnosis of malignant tumours of the digestive system, which can significantly improve the immediate and long-term results of their treatment.General ...
V. T. Ivashkin +20 more
doaj +1 more source
Gastroesophageal reflux disease and tooth erosion [PDF]
, 2011 The increasing prevalence of gastroesophageal reflux disease (GERD) in children and adults, and of “silent refluxers” in particular, increases the responsibility of dentists to be alert to this potentially severe condition when observing unexplained ...
Kaidonis, J., Ranjitkar, S., Smales, R.
core +4 more sources