Results 31 to 40 of about 133,403 (307)
Self Dilation of Esophageal Strictures
Canadian Journal of Gastroenterology, 1991 Over 22 years, 26 patients were taught to dilate their esophageal strictures. Fifteen had peptic strictures, four malignant neoplasms, three achalasia, three dysphagia following fundoplication and one esophageal lichen planus.
Stephen N Sullivan +2 more
doaj +1 more source
Российский журнал гастроэнтерологии, гепатологии, колопроктологии, 2019 Aim. The present guidelines intended for primary care physicians are aimed at facilitating early diagnosis of malignant tumours of the digestive system, which can significantly improve the immediate and long-term results of their treatment.General ...
V. T. Ivashkin +20 more
doaj +1 more source
The synchronous occurrence of squamous cell carcinoma and gastrointestinal stromal tumor (GIST) at esophageal site [PDF]
, 2008 Background Esophageal squamous cell carcinoma is a relative common malignancy with a very poor prognosis, even adopting an integrated and multidisciplinary approach.
Gian Spinelli +9 more
core +1 more source
The paradox of cancer genes in non-malignant conditions: implications for precision medicine. [PDF]
, 2020 Next-generation sequencing has enabled patient selection for targeted drugs, some of which have shown remarkable efficacy in cancers that have the cognate molecular signatures.
Adashek, Jacob J +3 more
core
Perspective review of what is needed for molecular-specific fluorescence-guided surgery [PDF]
, 2018 Molecular image-guided surgery has the potential for translating the tools of molecular pathology to real-time guidance in surgery. As a whole, there are incredibly positive indicators of growth, including the first United States Food and Drug ...
Achilefu, Samuel +3 more
core +4 more sources
Multiple Primary Malignancy of Esophageal and Gastric Synchronous and Colon Metachronous [PDF]
, 2017 Multiple primary cancer is an incidence when a patient has multiple Malignancy in two or more organs without possibility of metastatic lesion. There have been many reports on mutiple primary cancer since Billroth reported it for the first time in 1879 ...
Sugondo, L. A. (Lauretta) +1 more
core +1 more source
Eosinophilic fasciitis (Shulman's disease): review and comparative evaluation of seven patients. [PDF]
, 2019 OBJECTIVES: Eosinophilic fasciitis (EF) was described in 1974 by Shulman as a rare fibrosing connective tissue disease of unknown etiology. An undetermined trigger is thought to lead to the degranulation of eosinophils that interact with fibroblasts and
Cimbron, M +3 more
core +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
EZH2 Single Nucleotide Variants (SNVs): Diagnostic and Prognostic Role in 10 Solid Tumor Types [PDF]
, 2017 The enhancer of zeste homolog 2 (EZH2) gene encodes a histone methyltransferase that is a catalytic subunit of the Polycomb repressive complex 2 (PRC2) group of proteins that act to repress gene expression.
Crea, Francesco +4 more
core +2 more sources
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source