Results 41 to 50 of about 131,377 (348)

Multiple Primary Malignancy of Esophageal and Gastric Synchronous and Colon Metachronous [PDF]

, 2017
Multiple primary cancer is an incidence when a patient has multiple Malignancy in two or more organs without possibility of metastatic lesion. There have been many reports on mutiple primary cancer since Billroth reported it for the first time in 1879 ...
Sugondo, L. A. (Lauretta), Tenggara, R. (Riki)   +1 more
core   +1 more source

Correlated fragile site expression allows the identification of candidate fragile genes involved in immunity and associated with carcinogenesis [PDF]

, 2006
Common fragile sites (cfs) are specific regions in the human genome that are particularly prone to genomic instability under conditions of replicative stress. Several investigations support the view that common fragile sites play a role in carcinogenesis.
A Caputo, A Matsuyama, A Musio, Alda Maria Puliti, AM Casper, Angela Re, CD Hou, CT Miller, D Corà, D Corà, D Iliopoulos, Davide Cora, E Birney, H Ishii, I Sbrana, I Sbrana, Isabella Sbrana, ISCN, J Bartkova, J Hoshen, K Mimori, KA Cimprich, KA Nyberg, LV O'Keefe, M Ashburner, M Fabbri, M Schwartz, Michele Caselle, Newman MEJ, NS Chang, P Hoglund, RS Cha, S Corbin, S Gasser, SL Reiner, T Oyama, TW Glover, U Krummrei, VG Gorgoulis, Y Zhu   +39 more
core   +5 more sources

Recent Advances and the Potential for Clinical Use of Autofluorescence Detection of Extra-Ophthalmic Tissues [PDF]

, 2020
The autofluorescence (AF) characteristics of endogenous fluorophores allow the label-free assessment and visualization of cells and tissues of the human body.
Aigner, Felix, Pratschke, Johann, Schumann, Teresa, Stockmann, Martin, Tacke, Frank, Theil, Donna, Wizenty, Jonas, Wuensch, Tilo   +7 more
core   +1 more source

Breast radiation-associated secondary malignancies: A review

Clinical Surgical Oncology, 2023
Secondary malignancies are a late complication of radiation treatment for primary cancer through DNA damage. Specifically after breast cancer radiation, a number of tissues are vulnerable to radiation damage and have increased risk for developing ...
Sarah Poland, Wataru Ebina, Franco Muggia, Amber Guth   +3 more
doaj   +1 more source

Natural history of patients with non cirrhotic portal hypertension: Comparison with patients with compensated cirrhosis [PDF]

, 2018
Background. The knowledge of natural history of patients with portal hypertension (PH) not due to cirrhosis is less well known than that of cirrhotic patients. Aim.
Aprile, Francesca, Gioia, Stefania, Merli, Manuela, Nardelli, Silvia, Nicoletti, Valeria, Pasquale, Chiara, Pentassuglio, Ilaria, Riggio, Oliviero   +7 more
core   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

The paradox of cancer genes in non-malignant conditions: implications for precision medicine. [PDF]

, 2020
Next-generation sequencing has enabled patient selection for targeted drugs, some of which have shown remarkable efficacy in cancers that have the cognate molecular signatures.
Adashek, Jacob J, Kato, Shumei, Kurzrock, Razelle, Lippman, Scott M   +3 more
core  

Eosinophilic fasciitis (Shulman's disease): review and comparative evaluation of seven patients. [PDF]

, 2019
OBJECTIVES: Eosinophilic fasciitis (EF) was described in 1974 by Shulman as a rare fibrosing connective tissue disease of unknown etiology. An undetermined trigger is thought to lead to the degranulation of eosinophils that interact with fibroblasts and
Cimbron, M, Farinha, F, Mendonça, T, Urzal, J   +3 more
core   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source