Results 151 to 160 of about 13,002 (189)
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Physiology and Pathophysiology of the Lower Esophageal Sphincter

Annals of Otology, Rhinology & Laryngology, 1975
The physiologic factors controlling lower esophageal sphincter (LES) function are interrelated in a complex fashion and include the autonomic nerve supply, gastrointestinal hormones, and specific characteristics of the circular smooth muscle at the esophagogastric junction. It might be expected that a defect in any of these three controlling mechanisms
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Gastrin and Lower Esophageal Sphincter Tone

Archives of Internal Medicine, 1978
The gastrointestinal polypeptide gastrin, found in great abundance in the gastric antrium, was shown in 1970 to have a very dramatic effect in stimulating the smooth muscle segment of the lower esophageal sphincter (LES), and in causing marked increases in pressure in this region.
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Lower esophageal sphincter function in cirrhosis

The American Journal of Digestive Diseases, 1977
Lower esophageal sphincter (LES) function in cirrhosis was evaluated using an infused manometric system. LES pressure (LESP) in 10 subjects with cirrhosis (22 +/- 1 mm Hg) (mean +/- SE) was not significantly (P greater than 0.05) different from that of 10 control subjects (21 +/- 1 mm Hg) but was significantly (P less than 0.01) greater than the LESP ...
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Correlation of lower esophageal mucosal ring and lower esophageal sphincter pressure

Digestive Diseases and Sciences, 1994
We assessed the relationship of lower esophageal sphincter pressure (LESP) to presence and absence of lower esophageal mucosal ring (LEMR) in 66 patients to determine if the LEMR was more likely related to prolonged sphincter hypotension. This potential relationship is of interest because LEMR may be due to reflux esophagitis.
M Y, Chen   +4 more
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The Lower Esophageal Sphincter Shown by a Computerized Representation

Scandinavian Journal of Gastroenterology, 1990
The clinical application of manometry of the lower esophageal sphincter (LES) remains controversial. This is because of the large variability in recorded lower esophageal sphincter pressure (LESP). In this paper a computerized method providing a three-dimensional image of the LES is described.
Bemelman, W. A.   +4 more
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Hypertensive Lower Esophageal Sphincter: A Reappraisal

Southern Medical Journal, 1978
The hypertensive lower esophageal sphincter (LES) is defined as one with normal relaxation and an average LES-intragastric pressure gradient greater than or equal to 40 mm Hg. Case histories of two patients with hypertensive LES and normal peristalsis in the body of the esophagus are contrasted to that of a patient with a hypertensive LES and diffuse ...
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The hypertensive lower esophageal sphincter

Digestive Diseases and Sciences, 1989
Controversy exists as to whether the hypertensive lower esophageal sphincter (HLES) represents a clinical motility disorder of the esophagus or is merely the right-sided expression of a normal distribution curve. In the present study we describe 16 patients with HLES, defined as a lower esophageal sphincter (LES) pressure of greater than or equal to 40
N, Freidin   +3 more
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Idiopathic Lower Esophageal Sphincter Incompetence and Esophageal Stricture

Archives of Internal Medicine, 1980
Under normal circumstances, the lower esophageal sphincter (LES) acts as a pressure barrier at the gastroesophageal junction. When challenged by an increase in intra-abdominal pressure, the LES pressure correspondingly increases to maintain a dynamic equilibrium that prevents gastroesophageal reflux.
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Caffeine and the lower esophageal sphincter

The American Journal of Digestive Diseases, 1972
G W, Dennish, D O, Castell
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