Results 11 to 20 of about 79,389 (158)

Characteristic and Interplay of Esophageal Microbiota in Esophageal Squamous Cell Carcinoma [PDF]

BMC Cancer, 2021
Abstract Background: Esophageal squamous cell carcinoma(ESCC) is severe cancer in the world. The role of esophageal microbiota for ESCC is still uncertain. In the current study, 120 paired tissues from ESCC patients were collected, and 16s rRNA sequencing was performed to explore the esophageal microbiota.
Zheng Lin, Wenqing Rao, Zhisheng Xiang, Qiaoyan Zeng, Shuang Liu, Kaili Yu, Jinsong Zhou, Jianwen Wang, Weilin Chen, Yuanmei Chen, Xiane Peng, Zhijian Hu   +11 more
openaire   +3 more sources

Immunotherapy for Esophageal Squamous Cell Carcinoma [PDF]

Current Oncology Reports, 2017
Esophageal squamous cell carcinoma have been frustrating to treat, with slow progress made on extending survival. Immunotherapy targeting immune checkpoints, T cells, and infiltrating lymphocytes has shown promise in early studies. The efficacy of pembrolizumab and nivolumab is encouraging. Anti-chemokine receptors and oncolytic viruses are also making
Kojima, Takashi, Doi, Toshihiko
openaire   +2 more sources

Characterization of Esophageal Microbiota in Patients With Esophagitis and Esophageal Squamous Cell Carcinoma [PDF]

Frontiers in Cellular and Infection Microbiology, 2021
Microbial imbalances have been well elucidated in esophageal adenocarcinoma. However, few studies address the microbiota in esophageal squamous cell carcinoma (ESCC) and esophagitis (ES). We aimed to explore the association of esophageal microbiota with these patients.
Jiang Zongdan, jun wang, ziyang shen, zhenyu zhang, shukui Wang   +4 more
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Downregulation of Ubiquitin Inhibits the Aggressive Phenotypes of Esophageal Squamous Cell Carcinoma

Technology in Cancer Research & Treatment, 2020
Purpose: Esophageal cancer is one of the most common malignancies worldwide. Ubiquitin-dependent degradation of regulatory proteins reportedly plays a central role in diverse cellular processes.
Yi Gao MD, Wei Mo MD, Li Zhong MD, Huimin Jia MD, Yiren Xu BA, Ji Zhang BA, Xiaohui Xu MD, Weidong Shen PhD, Fangjun Wang PhD, Tengfei Li MD, Pengfei Liu PhD, Shuyu Zhang PhD   +11 more
doaj   +1 more source

NOTCH and Esophageal Squamous Cell Carcinoma

, 2020
Esophageal squamous cell carcinoma (ESCC) is a deadly disease that requires extensive research on its mechanisms, prevention, and therapy. Recent studies have shown that NOTCH mutations are commonly seen in human ESCC. This chapter summarizes our current understanding of the NOTCH pathway in normal esophagus and in ESCC.
Yong, Li, Yahui, Li, Xiaoxin, Chen
openaire   +3 more sources

Preliminary evaluation for Bit1 as a potential biomarker for squamous cell carcinoma and adenocarcinoma of esophagus

Tumor Biology, 2017
Mounting evidence has demonstrated that Bit1 has been investigated as an etiological factor for certain cancers, including esophageal squamous cell carcinoma reported in our previous study, but data regarding possible roles of Bit1 in esophageal squamous
Jing Chen, Hongtao Liu, Pan Gao, Yiran Hui, Zhenzhen Yang, Xiaqing Zhang, Peirong Xu, Fang Tian, Tianli Fan   +8 more
doaj   +1 more source

Semaphorin 3F Serves as a Tumor Suppressor in Esophageal Squamous Cell Carcinoma and is Associated With Lymph Node Metastasis in Disease Progression

Technology in Cancer Research & Treatment, 2020
Background: Esophageal squamous cell carcinoma is one of the leading aggressive malignancies with high mortality. Semaphorin 3F has been reported to be involved in lymphangiogenesis by interacting the vascular endothelial growth factor C/neuropilin 2 ...
Zhen Xie MD, Tianyue Li MD, Bingtao Huang MM, Shuai Liu MM, Lianguo Zhang MM, Qingguang Zhang MD   +5 more
doaj   +1 more source

promoter methylation is associated with prognosis in esophageal squamous cell carcinoma

Tumor Biology, 2017
Esophageal squamous cell carcinoma is a commonly malignant tumor of digestive tract with poor prognosis. Previous studies suggested that forkhead box F2 ( FOXF2 ) could be a candidate gene for assessing and predicting the prognosis of human cancers ...
Xiaoying Chen, Haochang Hu, Jing Liu, Yong Yang, Guili Liu, Xiuru Ying, Yingmin Chen, Bin Li, Cong Ye, Dongping Wu, Shiwei Duan   +10 more
doaj   +1 more source

Esophageal Squamous Cell Papilloma, Suspected of Squamous Cell Carcinoma.

Internal Medicine, 1993
A 46-year-old male without any subjective complaints was diagnosed by radiography as having one polypoid lesion at the distal esophagus. Endoscopy indicated a semipedunculated polyp about 1 cm in size, the specimens of which included atypical cells with a high N/C ratio in the submucosa.
YUKI, Takehiko, KAWANO, Sunao, OGIHARA, Tatsuo, SATO, Nobuhiro, OKAMOTO, Shigeru, SATO, Kenji, KAMADA, Takenobu, TAKADA, Naoki, FURUKAWA, Junko, OKAMURA, Jun   +9 more
openaire   +3 more sources

Clinicopathological significance of c-MYC in esophageal squamous cell carcinoma

Tumor Biology, 2017
Esophageal squamous cell carcinoma is one of the most common malignant tumors. The oncogene c-MYC is thought to be important in the initiation, promotion, and therapy resistance of cancer.
Yu Lian, Xiangdong Niu, Hui Cai, Xiaojun Yang, Haizhong Ma, Shixun Ma, Yupeng Zhang, Yifeng Chen   +7 more
doaj   +1 more source