Results 131 to 140 of about 5,331,742 (248)

Spatially Aware Acquisition‐Independent Deep Learning for IVIM MRI Parameter Estimation in Patients With Esophageal Cancer

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Neural controlled differential equations (NCDEs) recently emerged as a robust deep learning approach for quantitative MRI parameter estimation. NCDEs offer flexibility to changes in acquisition protocols by modeling the signal evolution dynamics. However, NCDE implementations operate on a voxel‐by‐voxel basis and cannot exploit spatial
Daan Kuppens, Roman S. Oort, Sebastiano Barbieri, Stella Mook, Gert J. Meijer, Oliver J. Gurney‐Champion   +5 more
wiley   +1 more source

Awake Blue Laser Excision and Balloon Dilation of Oropharyngeal Stenosis in High‐Risk Patients

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Oropharyngeal stenosis is a rare condition that can develop following head and neck cancer treatment, leading to progressive dyspnea, dysphagia, and dysphonia. Patients with symptomatic dyspnea may benefit from endoscopic surgery. However, head and neck cancer survivors can have severe trismus, limited neck extension, and altered laryngeal ...
Abbey L. Landini, Cyrus W. Abrahamson, Andrew P. Stein   +2 more
wiley   +1 more source

Frailty and Recovery Following Free Flap Reconstruction in Head and Neck Cancer: A Systematic Review

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To review the impact of frailty on various outcomes in geriatric head and neck cancer (HNC) patients undergoing microvascular free flap reconstruction (MFFR). Data Sources MEDLINE, Embase, and World of Science. Review Methods Following PRISMA guidelines, two independent reviewers performed a systematic review of MEDLINE, Embase, and ...
Anvitha R. Metpally, Mitchell T. Victor, Mirian Ramirez, Avinash Mantravadi, Michael W. Sim, Michael G. Moore, Jessica A. Yesensky, Janice L. Farlow   +7 more
wiley   +1 more source

Objective Swallowing Outcomes After Sparing Contralateral Low‐Neck Elective Radiotherapy in Oropharyngeal Carcinoma: Single‐Institution Clinical Experience

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective Dysphagia is a major toxicity of chemoradiation (CRT) for oropharyngeal squamous cell carcinoma (OPSCC). Elective upper‐neck irradiation (UNI), omitting the low neck, may reduce esophageal inlet muscle (EIM) dose and improve swallowing outcomes compared to elective whole‐neck irradiation (WNI).
Rex H. Lee, Cara Evans, Sarah Honjo, Yue Ma, Alon Witztum, Patrick K. Ha, Sue S. Yom, Jason W. Chan   +7 more
wiley   +1 more source

Deciphering diverse cell‐death patterns to predict the prognosis and potential therapy target of hepatocellular carcinoma patients

VIEW, EarlyView.
Abstract Ninety percent of all primary liver malignancies are hepatocellular carcinomas (HCC), making liver cancer the third most common cause of cancer‐associated mortality. Different patterns of programmed cell death (PCD) are crucial for the survival of tumors, and they might serve as a prognostic marker for HCC.
Lin Ding, Qian Li, Wenjing Yang, Te Liu, Tongtong Tian, Yu Liu, Chunyan Zhang, Baishen Pan, Beili Wang, Fan Wu, Wei Guo   +10 more
wiley   +1 more source

Apo10 and TKTL1 as novel liquid biopsy biomarkers for early detection of gastrointestinal malignancies

VIEW, EarlyView.
(A) Overview of the study population and schematic illustration showing tumor‐derived apoptotic and metabolic biomarkers, Apo10 and TKTL1, being phagocytosed by circulating monocytes and subsequently detected in peripheral blood. (B) Illustration of the epitope detection in monocytes (EDIM) strategy, using a flow‐cytometric gating approach based on ...
Zhiying Mao, Qiyu Huang, Juan Xiao, Ziyu Liu, Xinyan Zou, Yuying Liu, Lizhi Liu, Musheng Zeng, Chuanbo Xie   +8 more
wiley   +1 more source

Identification of STAT1 as a biomarker for lymph node metastasis in esophageal squamous cell carcinoma. [PDF]

J Mol Histol
Lv G, Li H, Lei Y, Peng J, Liu F, Zhao W.   +5 more
europepmc   +1 more source

Current Advances of Treatments, Therapeutic Targets, Biomarkers, Novel Drugs, and Machine Learning for Hypopharyngeal Squamous Cell Carcinoma

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Hypopharyngeal squamous cell carcinoma (HSCC) is an aggressive subtype of head and neck squamous cell carcinoma with insidious onset, early metastasis, and dismal prognosis. Conventional multimodal therapy achieves limited survival benefit, highlighting an urgent need for refined precision strategies.
Ce Li, Rui Guan, Rui‐Jie Jiao, Zhi‐Jie Bi, Yang Fu, Yin Wang, Chen‐Yang Xu, Ye Qian, Ran Wei, Sheng‐Da Cao, Wen‐Ming Li, Dong‐Min Wei, Da‐Peng Lei   +12 more
wiley   +1 more source

The Functional Role and Molecular Characterization of the Therapeutic Target CLDN6 in Germ Cell Tumors

Andrology, EarlyView.
ABSTRACT Background The tight junction protein CLDN6 has been identified as a cancer‐associated cell surface marker that is rarely expressed in healthy tissues. In testicular germ cell tumors (GCT), CLDN6 is particularly detectable in seminomas, embryonal carcinomas, and choriocarcinomas.
Jule Zwick, Margaretha A. Skowron, Gereon Poschmann, Patrick Petzsch, Ann Kathrin Bergmann, Kai Stühler, Jochen Hecht, Daniel Nettersheim   +7 more
wiley   +1 more source

A rare case report on esophageal squamous cell carcinoma metastatic to the colon. [PDF]

Front Oncol
Hu L, Zha Y, Li C, Huang M, Yuan Q, Wu Y, Cheng W.   +6 more
europepmc   +1 more source