Results 1 to 10 of about 17,054 (153)
An overview of downhill esophageal varices: a challenge for medical practice [PDF]
Annals of MedicineObjectives Unlike the commonly seen uphill esophageal varices in clinical practice, downhill esophageal varices are caused by obstruction of the superior vena cava and azygous venous system.
Donghong Wang, Zhibin Ma
doaj +2 more sources
Platelet Count/Spleen Diameter Ratio and Serum Ascites Albumin Gradient for Screening Parameters of Esophageal Varices in Decompensated Hepatic Cirrhosis: An Observational Study [PDF]
Journal of Nepal Medical AssociationIntroduction: In low- and middle-income countries like Nepal, with limited resources, the oesophagogastroduodenoscopy facility may not be available widely due to its high cost and availability constraints.
Rinku Joshi +5 more
doaj +2 more sources
Can “Attenuation Subtraction”, a Computed Tomography Scan‐Based Factor, be Used as a Predictor of High‐Risk Esophageal Varices in Cirrhotic Patients? A Retrospective Cohort Study [PDF]
Health Science ReportsBackground and Aims Liver cirrhosis is a severe condition that can result in complications such as portal hypertension and esophageal varices (EVs). While current guidelines recommend screening for EVs, existing procedures are often invasive, costly, and
Mohammad Mersad Mansouri Tehrani +6 more
doaj +2 more sources
Journal of Nobel Medical College, 2022 Background: In patients with chronic liver diseases, liver and spleen stiffness measurement by elastography is the most recent available noninvasive tool.
Pratap Sagar Tiwari, Sudhamshu KC
doaj +1 more source
F1000Research, 2021 Background: Bleeding from esophageal varices is a life-threatening complication in cirrhosis. Screening endoscopy is recommended in cirrhotic patients to identify patients at risk of variceal hemorrhage, but this is an invasive procedure and has ...
Anum Afsar +5 more
doaj +1 more source
Hepatology, EarlyView., 2022 A deleterious variant of FCHSD1 results in mTOR pathway overactivation and may cause porto‐sinusoidal vascular disorder (PSVD). The pedigree of the family demonstrated an autosomal dominant disease with variable expressivity. Whole‐genome sequencing and Sanger sequencing both validated the existence of the FCHSD1 variant and the heterozygosity of c ...
Jingxuan Shan +19 more
wiley +1 more source
Janus kinase 2 inhibition by pacritinib as potential therapeutic target for liver fibrosis
Hepatology, EarlyView., 2022 Diagram of the activation of the profibrotic and procontractile Janus kinase 2 (JAK2)/Ras homolog family member A/Rho‐kinase pathway and the inhibition of phosphorylated JAK2 by pacritinib to inhibit hepatic stellate cell activity. Abstract Background and Aims Janus kinase 2 (JAK2) signaling is increased in human and experimental liver fibrosis with ...
Sandra Torres +21 more
wiley +1 more source
Medicina, 2022 Background and Objectives: Balloon-occluded retrograde transvenous obliteration (BRTO) could be currently one of the best therapies for patients with gastric varices.
Taku Mizutani +9 more
doaj +1 more source
Hepatology, EarlyView., 2022 Natural history of liver disease in a large international cohort of children with Alagille syndrome: Results from the GALA study. Abstract Background and Aims Alagille syndrome (ALGS) is a multisystem disorder, characterized by cholestasis. Existing outcome data are largely derived from tertiary centers, and real‐world data are lacking.
Shannon M. Vandriel +93 more
wiley +1 more source
Interleukin‐18 signaling promotes activation of hepatic stellate cells in mouse liver fibrosis
Hepatology, EarlyView., 2022 Interleukin‐18 signaling promotes activation of hepatic stellate cells in mouse liver fibrosis. Abstract Background and Aims Nucleotide‐binding oligomerization domain‐like receptor‐family pyrin domain‐containing 3 (NLRP3) inflammasome activation has been shown to result in liver fibrosis.
Jana Knorr +19 more
wiley +1 more source