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The Role of Endoscopic Ultrasound for Esophageal Varices
Esophageal varices are caused by the development of collateral circulation in the esophagus as a result of portal hypertension. It is important to administer appropriate preventive treatment because bleeding varices can be fatal.
Kazunori Nagashima+11 more
doaj +2 more sources
An overview of downhill esophageal varices: a challenge for medical practice [PDF]
Objectives Unlike the commonly seen uphill esophageal varices in clinical practice, downhill esophageal varices are caused by obstruction of the superior vena cava and azygous venous system.
Donghong Wang, Zhibin Ma
doaj +2 more sources
Evaluation of endoscopic secondary prophylaxis in children and adolescents with esophageal varices
BACKGROUND Bleeding of esophageal varices is the main cause of morbidity and mortality in children and adults with portal hypertension and there are few studies involving secondary prophylaxis in children and adolescents.
Júlio Rocha PIMENTA+5 more
doaj +2 more sources
Relationship Between Child Turcotte Pugh (CTP) Score and Esophageal Varices (EV) Among Sudanese Cirrhotic Patients in Wad Madani Teaching Hospital, 2024: A Cross-Sectional Study. [PDF]
ABSTRACT Background Esophageal varices (EV) are a fatal complication of cirrhosis. The guidelines suggest that esophageal varices should be diagnosed before bleeding in all patients. In patients with cirrhosis, the Child Turcotte Pugh (CTP) class has been used as a prognostic tool for variceal bleeding.
Elsiddig E+3 more
europepmc +2 more sources
Can “Attenuation Subtraction”, a Computed Tomography Scan‐Based Factor, be Used as a Predictor of High‐Risk Esophageal Varices in Cirrhotic Patients? A Retrospective Cohort Study [PDF]
Background and Aims Liver cirrhosis is a severe condition that can result in complications such as portal hypertension and esophageal varices (EVs). While current guidelines recommend screening for EVs, existing procedures are often invasive, costly, and
Mohammad Mersad Mansouri Tehrani+6 more
doaj +2 more sources
Background: In patients with chronic liver diseases, liver and spleen stiffness measurement by elastography is the most recent available noninvasive tool.
Pratap Sagar Tiwari, Sudhamshu KC
doaj +1 more source
Background: Bleeding from esophageal varices is a life-threatening complication in cirrhosis. Screening endoscopy is recommended in cirrhotic patients to identify patients at risk of variceal hemorrhage, but this is an invasive procedure and has ...
Anum Afsar+5 more
semanticscholar +1 more source
A deleterious variant of FCHSD1 results in mTOR pathway overactivation and may cause porto‐sinusoidal vascular disorder (PSVD). The pedigree of the family demonstrated an autosomal dominant disease with variable expressivity. Whole‐genome sequencing and Sanger sequencing both validated the existence of the FCHSD1 variant and the heterozygosity of c ...
Jingxuan Shan+19 more
wiley +1 more source
Janus kinase 2 inhibition by pacritinib as potential therapeutic target for liver fibrosis
Diagram of the activation of the profibrotic and procontractile Janus kinase 2 (JAK2)/Ras homolog family member A/Rho‐kinase pathway and the inhibition of phosphorylated JAK2 by pacritinib to inhibit hepatic stellate cell activity. Abstract Background and Aims Janus kinase 2 (JAK2) signaling is increased in human and experimental liver fibrosis with ...
Sandra Torres+21 more
wiley +1 more source
Natural history of liver disease in a large international cohort of children with Alagille syndrome: Results from the GALA study. Abstract Background and Aims Alagille syndrome (ALGS) is a multisystem disorder, characterized by cholestasis. Existing outcome data are largely derived from tertiary centers, and real‐world data are lacking.
Shannon M. Vandriel+93 more
wiley +1 more source