Results 61 to 70 of about 247,613 (254)

DOCK8 deficiency presenting with sclerosing cholangitis, raised immunoglobulin E, and bronchiectasis: A fatal pediatric case report

JPGN Reports, EarlyView.
Abstract Dedicator of cytokinesis 8 (DOCK8) deficiency is a rare autosomal recessive primary immunodeficiency. Patients with DOCK8 deficiency typically present at early age with allergic manifestations, cutaneous and respiratory infections, raised immunoglobulin E, and they have an increased risk of developing malignancies.
Natalia Nedelkopoulou, Kelechi Ugonna, Stephen Hughes, Sanjay Rajwal, Marumbo Mtegha   +4 more
wiley   +1 more source

Platelet Count/Spleen Diameter Ratio and Serum Ascites Albumin Gradient for Screening Parameters of Esophageal Varices in Decompensated Hepatic Cirrhosis: An Observational Study

Journal of Nepal Medical Association
Introduction: In low- and middle-income countries like Nepal, with limited resources, the oesophagogastroduodenoscopy facility may not be available widely due to its high cost and availability constraints.
Rinku Joshi, Kushal Shrestha, Sunil Shrestha, Sujeeta Bajracharya, Krishti Thapa, Sitaram Khadka   +5 more
doaj   +1 more source

Serum Growth Differentiation Factor 15 Can Be a Novel Biomarker to Predict the Prognosis of Patients With Hepatitis C Virus Cirrhosis After Virus Elimination

Hepatology Research, EarlyView.
ABSTRACT Background and Aims Although direct‐acting antivirals (DAAs) achieve high sustained virologic response (SVR) rates, the long‐term outcomes of patients with hepatitis C virus (HCV)‐related cirrhosis remain variable. Growth differentiation factor 15 (GDF15), a stress‐induced cytokine, has emerged as a potential biomarker for liver disease ...
Yuta Myojin, Hayato Hikita, Yuki Tahata, Kenji Fukumoto, Seiya Kato, Yoichi Sasaki, Shusuke Kumazaki, Atsunori Tsuchiya, Masaru Enomoto, Daiki Miki, Hiroshi Yatsuhashi, Hidekatsu Kuroda, Yoshihito Uchida, Hitoshi Yoshiji, Taro Yamashita, Seiichi Mawatari, Nobuharu Tamaki, Hisamitsu Miyaaki, Yasuhiro Asahina, Goki Suda, Kentaro Matsuura, Yasunari Nakamoto, Yoichi Hiasa, Taro Takami, Kumiko Shirai, Kazuki Maesaka, Kazuhiro Murai, Yuki Makino, Yoshinobu Saito, Takahiro Kodama, Tomohide Tatsumi, Tetsuo Takehara   +31 more
wiley   +1 more source

Development of Fundal Varices in Cirrhotic Patients after Eradication of Esophageal Varices

Journal of Rawalpindi Medical College, 2017
Background: To analyze the development of fundal varices in cirrhotic patients after eradication of esophageal varices Methods: In this observational study 150 patients of liver cirrhosis, with the history of upper gastrointestinal tract bleed and ...
Muhammad Ajmal
doaj  

Frailty Is an Independent Predictor of Mortality in Japanese Patients With Chronic Liver Disease: A Multicenter Retrospective Cohort Study

Hepatology Research, EarlyView.
ABSTRACT Aim Frailty is emerging as a prognostic factor in chronic liver disease (CLD). However, its clinical impact remains underexplored, particularly in Japan. This study aimed to evaluate the prognostic significance of frailty in Japanese patients with CLD.
Shinji Unome, Mikita Oi, Yuki Utakata, Takao Miwa, Masashi Aiba, Tatsunori Hanai, Makoto Shiraki, Yasuhiro Kawashima, Naoki Katsumura, Masahito Shimizu   +9 more
wiley   +1 more source

Effect of General Anesthesia on Liver and Spleen Stiffness for Predicting High‐Risk Varices in Biliary Atresia

Hepatology Research, EarlyView.
In children with biliary atresia (BA), breath‐holding during liver and spleen stiffness (LS and SS) measurement is often difficult, raising concerns about measurement reliability in the awake state. We investigated whether performing LS and SS measurements under general anesthesia—when brief ventilation pauses are possible—could improve diagnostic ...
Shinya Yokoyama, Takashi Honda, Yoji Ishizu, Norihiro Imai, Takanori Ito, Kenta Yamamoto, Chiyoe Shirota, Takahisa Tainaka, Satoshi Makita, Masanao Nakamura, Hiroo Uchida, Hiroki Kawashima   +11 more
wiley   +1 more source

The Baveno VI criteria for predicting esophageal varices: validation in real life practice.

Revista Espanola de Enfermedades Digestivas, 2017
BACKGROUND AND AIMS According to the Baveno VI consensus, patients with liver stiffness < 20 kPa and a platelet count > 150,000 ul have very low risk of clinically significant varices and do not need a screening endoscopy.
M. Sousa, S. Fernandes, L. Proença, A. Silva, S. Leite, Joana Silva, A. Ponte, J. Rodrigues, João-Carlos Silva, J. Carvalho   +9 more
semanticscholar   +1 more source

Comparison effectiveness of topical analgesics with and without Entonox for esophagogastroduodenoscopy: A randomized controlled trial

DEN Open, Volume 6, Issue 1, April 2026.
Abstract Objectives Esophagogastroduodenoscopy (EGD) is vital for diagnosing and treating upper gastrointestinal symptoms, but patient discomfort and anxiety can affect procedural outcomes. This study aimed to compare the effectiveness of topical analgesics with and without Entonox during EGD in terms of procedural success, patient tolerance, and ...
Papiroon Noitasaeng, Uayporn Kaosombatwattana, Rojsirin Chaiwong, Phongthara Vichitvejpaisal   +3 more
wiley   +1 more source

Prediction of large esophageal varices in cirrhotic patients using classification and regression tree analysis

Clinics, 2011
OBJECTIVES: Recent guidelines recommend that all cirrhotic patients should undergo endoscopic screening for esophageal varices. That identifying cirrhotic patients with esophageal varices by noninvasive predictors would allow for the restriction of the ...
Wan-dong Hong, Le-mei Dong, Zen-cai Jiang, Qi-huai Zhu, Shu-Qing Jin   +4 more
doaj  

Endoscopic Ultrasonography‐guided Variceal Therapy as Salvage Treatment for Rebleeding From Duodenal Varices Following Balloon‐occluded Retrograde Transvenous Obliteration

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Duodenal varices, though rare, are potentially life‐threatening complications of portal hypertension. Management is challenging when balloon‐occluded retrograde transvenous obliteration (BRTO) fails to achieve complete obliteration. Endoscopic ultrasonography‐guided variceal therapy (EUS‐VT) is effective for gastric varices, but reports of ...
Sakue Masuda, Atsushi Irisawa, Soichiro Nakaya, Jun Kubota, Karen Kimura, Makomo Makazu, Kazuya Koizumi   +6 more
wiley   +1 more source