Results 71 to 80 of about 245,848 (265)

Mitochondrial Oxidative Stress in Circulating Leukocytes as a Prognostic Marker in Hepatocellular Carcinoma

Hepatology Research, EarlyView.
ABSTRACT Background and Aims The relationship between oxidative stress (OS) and hepatocellular carcinoma (HCC) is well known, influencing both, hepatocarcinogenesis and subsequent tumor progression. Less understood is its potential role in antitumor defense mechanisms.
Víctor Merino, Carlos Abril, Gloria Segarra, Maria Pilar Ballester, Joan Tosca, Pilar Aguilar, Pascual Medina, Paloma Lluch   +7 more
wiley   +1 more source

Prediction of large esophageal varices in cirrhotic patients using classification and regression tree analysis

Clinics, 2011
OBJECTIVES: Recent guidelines recommend that all cirrhotic patients should undergo endoscopic screening for esophageal varices. That identifying cirrhotic patients with esophageal varices by noninvasive predictors would allow for the restriction of the ...
Wan-dong Hong, Le-mei Dong, Zen-cai Jiang, Qi-huai Zhu, Shu-Qing Jin   +4 more
doaj  

Serum Growth Differentiation Factor 15 Can Be a Novel Biomarker to Predict the Prognosis of Patients With Hepatitis C Virus Cirrhosis After Virus Elimination

Hepatology Research, EarlyView.
ABSTRACT Background and Aims Although direct‐acting antivirals (DAAs) achieve high sustained virologic response (SVR) rates, the long‐term outcomes of patients with hepatitis C virus (HCV)‐related cirrhosis remain variable. Growth differentiation factor 15 (GDF15), a stress‐induced cytokine, has emerged as a potential biomarker for liver disease ...
Yuta Myojin, Hayato Hikita, Yuki Tahata, Kenji Fukumoto, Seiya Kato, Yoichi Sasaki, Shusuke Kumazaki, Atsunori Tsuchiya, Masaru Enomoto, Daiki Miki, Hiroshi Yatsuhashi, Hidekatsu Kuroda, Yoshihito Uchida, Hitoshi Yoshiji, Taro Yamashita, Seiichi Mawatari, Nobuharu Tamaki, Hisamitsu Miyaaki, Yasuhiro Asahina, Goki Suda, Kentaro Matsuura, Yasunari Nakamoto, Yoichi Hiasa, Taro Takami, Kumiko Shirai, Kazuki Maesaka, Kazuhiro Murai, Yuki Makino, Yoshinobu Saito, Takahiro Kodama, Tomohide Tatsumi, Tetsuo Takehara   +31 more
wiley   +1 more source

Frailty Is an Independent Predictor of Mortality in Japanese Patients With Chronic Liver Disease: A Multicenter Retrospective Cohort Study

Hepatology Research, EarlyView.
ABSTRACT Aim Frailty is emerging as a prognostic factor in chronic liver disease (CLD). However, its clinical impact remains underexplored, particularly in Japan. This study aimed to evaluate the prognostic significance of frailty in Japanese patients with CLD.
Shinji Unome, Mikita Oi, Yuki Utakata, Takao Miwa, Masashi Aiba, Tatsunori Hanai, Makoto Shiraki, Yasuhiro Kawashima, Naoki Katsumura, Masahito Shimizu   +9 more
wiley   +1 more source

Diagnostic performance of ARFI ultrasound elastography in spleen stiffness measurement to predict esophageal varices [PDF]

Al Ameen Journal of Medical Sciences, 2022
Background: Presence esophageal varices are an independent predictor of mortality in patients with cirrhosis. Non-invasive assessment of cirrhotic patients to predict esophageal varices have been increasingly used instead of endoscopy.
Mahesh Seetharam, Rajendra Kumar L. Narasipur, Vinaya M. Gowda, Pradeep N. Hagalahalli, Nanjaraj P. Chakenahalli, Muralidhara P. Chennagiri   +5 more
doaj  

Effect of General Anesthesia on Liver and Spleen Stiffness for Predicting High‐Risk Varices in Biliary Atresia

Hepatology Research, EarlyView.
In children with biliary atresia (BA), breath‐holding during liver and spleen stiffness (LS and SS) measurement is often difficult, raising concerns about measurement reliability in the awake state. We investigated whether performing LS and SS measurements under general anesthesia—when brief ventilation pauses are possible—could improve diagnostic ...
Shinya Yokoyama, Takashi Honda, Yoji Ishizu, Norihiro Imai, Takanori Ito, Kenta Yamamoto, Chiyoe Shirota, Takahisa Tainaka, Satoshi Makita, Masanao Nakamura, Hiroo Uchida, Hiroki Kawashima   +11 more
wiley   +1 more source

Advances in the treatment of hepatocellular carcinoma: An overview of the current and evolving therapeutic landscape for clinicians

CA: A Cancer Journal for Clinicians, EarlyView.
Abstract Hepatocellular carcinoma (HCC) is the sixth most common malignancy and the third leading cause of cancer‐related death worldwide. Contemporary advances in systemic and locoregional therapies have led to changes in peer‐reviewed guidelines regarding systemic therapy as well as the possibility of downstaging disease that may enable some patients
Dimitrios Moris, Alessandro Martinino, Sarah Schiltz, Peter J. Allen, Andrew Barbas, Debra Sudan, Lindsay King, Carl Berg, Charles Kim, Mustafa Bashir, Manisha Palta, Michael A. Morse, Michael E. Lidsky   +12 more
wiley   +1 more source

Comparison effectiveness of topical analgesics with and without Entonox for esophagogastroduodenoscopy: A randomized controlled trial

DEN Open, Volume 6, Issue 1, April 2026.
Abstract Objectives Esophagogastroduodenoscopy (EGD) is vital for diagnosing and treating upper gastrointestinal symptoms, but patient discomfort and anxiety can affect procedural outcomes. This study aimed to compare the effectiveness of topical analgesics with and without Entonox during EGD in terms of procedural success, patient tolerance, and ...
Papiroon Noitasaeng, Uayporn Kaosombatwattana, Rojsirin Chaiwong, Phongthara Vichitvejpaisal   +3 more
wiley   +1 more source

Incidence of HCV induced—Esophageal varices in Egypt

Medicine, 2017
Esophageal varices is one of the most important comorbidity related liver cirrhosis, patients usually presented with hematemesis, melena, or both, ultimately 20% is the mortality during the first attack, hence we aimed to investigate the incidence of ...
M. Abdel-Aty, M. Fouad, M. Sallam, E. A. Elgohary, A. Ismael, A. Nawara, B. Hawary, M. Tag-Adeen, S. Khaled   +8 more
semanticscholar   +1 more source

Endoscopic Ultrasonography‐guided Variceal Therapy as Salvage Treatment for Rebleeding From Duodenal Varices Following Balloon‐occluded Retrograde Transvenous Obliteration

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Duodenal varices, though rare, are potentially life‐threatening complications of portal hypertension. Management is challenging when balloon‐occluded retrograde transvenous obliteration (BRTO) fails to achieve complete obliteration. Endoscopic ultrasonography‐guided variceal therapy (EUS‐VT) is effective for gastric varices, but reports of ...
Sakue Masuda, Atsushi Irisawa, Soichiro Nakaya, Jun Kubota, Karen Kimura, Makomo Makazu, Kazuya Koizumi   +6 more
wiley   +1 more source