Results 101 to 110 of about 42,433 (281)

Mepolizumab Effectiveness in Severe Asthma With/Without Chronic Rhinosinusitis With Nasal Polyps: Real‐World Pooled Analysis

Allergy, EarlyView.
MEPOLYP was a pooled analysis of 1037 patients with SAEP[±]CRSwNP. Mepolizumab was associated with a reduction in CSEs, OCS use, and BEC, and improved lung function and ACT score. Over 47% of patients fulfilled ≥ 3 clinical remission criteria. When compared, there was a 30.0% incremental benefit of mepolizumab in reducing CSEs for patients with SAEP ...
Florence Schleich, Stelios Loukides, Rekha Chaudhuri, Joerg D. Leuppi, Enrico Heffler, Cristian Domingo, Claudio Micheletto, Thomas Paulsson, Nina Gaw, Konstantina Kallinikou, Carla Vossen, Florent Guelfucci, Jyothi Menon, Armel Ngami, Ines Palomares   +14 more
wiley   +1 more source

Does Patient Sex Influence the Symptom Pattern for Patients With Gastro‐Oesophageal Reflux Disease and the Response of Symptoms to Fundoplication?

ANZ Journal of Surgery, EarlyView.
ABSTRACT Background Several studies show that female patients experience lower satisfaction after anti‐reflux surgery. We hypothesised that there is a pattern of symptoms common to female patients presenting with GORD and that it is these symptoms in particular that lead to inferior outcomes.
Joshua N. Hammerschlag, Ross H. Roberts, Andrew McCombie   +2 more
wiley   +1 more source

Systematic Review: Variability in Definitions of Fibrostenosis in Eosinophilic Oesophagitis

Alimentary Pharmacology &Therapeutics, EarlyView.
Significant variability exists in definitions and diagnostic methods of detection regarding fibrostenosis in eosinophilic oesophagitis. Lack of consensus poses a barrier in clinical care and research. ABSTRACT Background Fibrostenosis is a serious complication of eosinophilic oesophagitis, but there is a lack of consensus regarding its definition and ...
Claire A. Beveridge, Natalie Farha, Christina Hermanns, Chiara Maruggi, Katherine Falloon, Shivani Thanawala, Mary Pat Harnegie, J. Mark Brown, Andrei I. Ivanov, Evan S. Dellon, Gary W. Falk, Christopher Ma, Nirmala Gonsalves, Anthony Lembo, Amanda B. Muir, Scott Gabbard, Glenn T. Furuta, Florian Rieder   +17 more
wiley   +1 more source

Combined Lyon and Milan Scores Predict Gerd Management Outcome Better Than Either Score Alone or Their Individual Components

Alimentary Pharmacology &Therapeutics, EarlyView.
The Lyon and Milan scores outperformed AET and DeMeester score in predicting outcomes in GERD patients. When concordant, they provide optimal predictive accuracy, guiding escalation of therapy. ABSTRACT Background Confidence in gastro‐oesophageal reflux disease (GERD) diagnosis is crucial to improve outcomes from escalation of treatment. The Lyon score
Stefano Siboni, Marco Sozzi, Pierfrancesco Visaggi, Sara Boveri, Benjamin D. Rogers, Nicola De Bortoli, Anthony Hobson, Brian E. Louie, Yeong Yeh Lee, Salvatore Tolone, Elisa Marabotto, Jordan Haworth, Megan L. Ivy, Lorenzo Cusmai, Edoardo Campioli, Dimitrios Theodorou, Tania Triantafyllou, Andrea Pasta, Francesco Calabrese, Vincent Tee, Daniele Bernardi, Carlo Galdino Riva, Roberta De Maron, Enrique Coss‐Adame, Amit Patel, Emanuele Asti, Edoardo Savarino, C. Prakash Gyawali   +27 more
wiley   +1 more source

Esophagitis in a Post‐Liver Transplant Patient: A Case of Cytomegalovirus and Herpes Simplex Virus‐1 Coinfection

Clinical Case Reports
In post‐liver transplant patients, esophagitis presents a diagnostic and management challenge due to the potential for opportunistic infections. This case describes a 59‐year‐old female with primary sclerosing cholangitis who underwent orthotopic liver ...
Ammad Javaid Chaudhary, Taher Jamali, Abdullah Sohail, Christian E. Keller, Allyce Caines, Mazen ELatrache   +5 more
doaj   +1 more source

Soybean Oil in Propofol Is Not Able to Induce Allergic Reactions

Allergy, EarlyView.
Deniz Eyice Karabacak, Lisa Arzt‐Gradwohl, Barbara Binder, Eva Schadelbauer, Christina Vallant, Karin Laipold, Gunter J. Sturm   +6 more
wiley   +1 more source

Treatment options for immune‐related adverse events associated with immune checkpoint inhibitors

British Journal of Pharmacology, EarlyView.
Abstract The immunotherapy revolution with the use of immune checkpoint inhibitors (ICIs) started with the clinical use of the first ICI, ipilimumab, in 2011. Since then, the field of ICI therapy has rapidly expanded — with the FDA approval of 10 different ICI drugs so far and their incorporation into the therapeutic regimens of a range of malignancies.
Yu Hua Chen, Tamás Kovács, Péter Ferdinandy, Zoltán V. Varga   +3 more
wiley   +1 more source

Dupilumab Efficacy and Safety in Patients With Persistent Asthma: Asia–Pacific Region

Clinical &Experimental Allergy, EarlyView.
Asthma prevalence is increasing in the Asia–Pacific region, and this population is frequently underrepresented in phase 3 clinical studies. We demonstrate Dupilumab's efficacy and safety among patients with uncontrolled moderate‐to‐severe type 2 asthma.
Qingling Zhang, Nanshan Zhong, Sahajal Dhooria, Xiuhua Fu, Haohui Fang, Jie Lin, Shuyang Zhu, Elizabeth Laws, Yi Wang, Vivian Li, Chih‐Chi Hu, Jennifer Maloney, Raolat M. Abdulai, Lacey B. Robinson   +13 more
wiley   +1 more source

Esophageal Melanocytosis

Autopsy Case Reports
Esophageal melanocytosis is a rare entity defined by the proliferation of a melanocytic basal layer of the esophageal squamous lining and deposition of melanin in the esophageal mucosa. Esophageal melanocytosis is considered a benign entity of unknown etiology; however, it has been reported as a melanoma precursor.
Samikshya Thapa, Gajendra Kumar Yadav, Ratna Mondal, Ravi Hari Phulware   +3 more
openaire   +3 more sources

Immunophenotyping in Vernal Keratoconjunctivitis: Schirmer Test for Therapy Response Prediction

Allergy, EarlyView.
Maria Teresa Bilotta, Paola Vacca, Mariacristina Esposito, Luca Buzzonetti, Giuseppe Bianco, Alessandro Giovanni Fiocchi, Lorenzo Moretta, Massimiliano Raponi, Maria Cristina Artesani, Nicola Tumino   +9 more
wiley   +1 more source