Results 121 to 130 of about 74,143 (357)

Chinese Guidelines for Diagnosis and Treatment of Chronic Rhinosinusitis (2024)

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Chronic rhinosinusitis (CRS), a complex inflammatory disease with heterogeneous pathogenesis, demands evolving evidence‐based strategies. Since the 2018 Chinese guidelines and EPOS2020, international advances in CRS immunopathology and biologics have revolutionized therapeutic approaches, particularly through phenotype–endotype classification ...
Subspecialty Group of Rhinology   +4 more
wiley   +1 more source

MicroRNAs in lung cancer [PDF]

open access: yes, 2017
Lung cancer (LC) is a serious public health problem responsible for the majority of cancer deaths and comorbidities in developed countries. Tobacco smoking is considered the main risk factor for LC; however, only a few smokers will be affected by this ...
An   +40 more
core   +1 more source

From Reflux Esophagitis to Esophageal Adenocarcinoma [PDF]

open access: yesDigestive Diseases, 2016
Reflux esophagitis causes Barrett's metaplasia, an abnormal esophageal mucosa predisposed to adenocarcinoma. Medical therapy for reflux esophagitis focuses on decreasing gastric acid production with proton pump inhibitors. We have reported that reflux esophagitis in a rat model develops from a cytokine-mediated inflammatory injury, not from a caustic ...
openaire   +2 more sources

Hiatoplasty with crura buttressing versus hiatoplasty alone during laparoscopic sleeve gastrectomy [PDF]

open access: yes, 2017
Introduction. In obese patients with hiatal hernia (HH), laparoscopic sleeve gastrectomy (LSG) with cruroplasty is an option but use of prosthetic mesh crura reinforcement is debated.
Badiali, Danilo   +6 more
core   +3 more sources

Isolated Anti‐SS‐A Antibody Seropositivity as a Poor Prognostic Factor in Systemic Sclerosis: Insights From a Cohort of 307 Cases

open access: yesThe Journal of Dermatology, EarlyView.
ABSTRACT Systemic sclerosis is an autoimmune disease characterized by vasculopathy, fibrosis, and immune dysregulation. Anti‐SS‐A antibodies (anti‐SSA) have been reported to confer severe clinical manifestations in some Western and Japanese cohorts. We aimed to determine whether anti‐SSA seropositivity affects clinical outcomes in Japanese patients. We
Nana Ishida   +4 more
wiley   +1 more source

The Effectiveness of Data Augmentation for Detection of Gastrointestinal Diseases from Endoscopical Images

open access: yes, 2017
The lack, due to privacy concerns, of large public databases of medical pathologies is a well-known and major problem, substantially hindering the application of deep learning techniques in this field.
Asperti, Andrea, Mastronardo, Claudio
core   +1 more source

Stratum Corneum Ceramide Abnormalities in Atopic Dermatitis: Pathophysiology and Implications for Disease Management

open access: yesThe Journal of Dermatology, EarlyView.
ABSTRACT The stratum corneum, as the outermost layer of the skin, functions as a critical barrier that maintains cutaneous hydration and systemic homeostasis. Among its structural lipids, ceramides constitute the most abundant and diverse component. These molecules are essential for the formation of lamellar structures that secure barrier integrity ...
Takashi Sakai
wiley   +1 more source

Esomeprazole for the treatment of erosive esophagitis in children: an international, multicenter, randomized, parallel-group, double-blind (for dose) study

open access: yesBMC Pediatrics, 2010
Background Acid suppression with a proton pump inhibitor is standard treatment for gastroesophageal reflux disease and erosive esophagitis in adults and increasingly is becoming first-line therapy for children aged 1-17 years.
Youssef Nader N   +4 more
doaj   +1 more source

Probabilistic analysis of cost-effectiveness models: choosing between treatment strategies for gastroesophageal reflux disease [PDF]

open access: yes, 2002
When choosing between mutually exclusive treatment options, it is common to construct a cost-effectiveness frontier on the cost-effectiveness plane that represents efficient points from among the treatment choices.
Blackhouse, G.   +3 more
core   +1 more source

Functional luminal imaging probe topography: an improved method for characterizing esophageal distensibility in eosinophilic esophagitis [PDF]

open access: bronze, 2012
Zhiyue Lin   +6 more
openalex   +1 more source

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