Results 141 to 150 of about 21,010 (265)

Adaptive Seamless Phase II/III Randomization Test Considering Treatment Group Selection Based on Short–Term Binary Outcomes

Statistics in Medicine, Volume 45, Issue 3-5, February 2026.
ABSTRACT Recently, adaptive seamless phase II/III designs (ASDs) have gained attention because they improve the efficiency of drug development. In an ASD, a phase II trial, which explores the dose–response relationships and identifies treatments for the phase III trial, is combined with a phase III trial, which aims to demonstrate the efficacy and ...
Funato Sato, Kohei Uemura, Junki Mizusawa, Yutaka Matsuyama, Yoshihiko Morikawa   +4 more
wiley   +1 more source

Refining pathological evaluation of neoadjuvant therapy for adenocarcinoma of the esophagus

, 2013
AIM: To assess tumour regression grade (TRG) and lymph node downstaging to help define patients who benefit from neoadjuvant chemotherapy.METHODS: Two hundred and eighteen consecutive patients with adenocarcinoma of the esophagus or gastro-esophageal ...
Bailey, Ian, Bateman, Adrian C., Bateman, Andrew R., Byrne, James, Iveson, T., Kelly, Jamie, Noble, Fergus, Nolan, Luke, Rees, Charlotte, Sharland, Donna, Underwood, T.J.   +10 more
core   +1 more source

A Novel Intra‐Operative Irrigation‐Drainage System for Robot‐Assisted Thoracoscopic Esophagogastric Layered Anastomosis: Preliminary Practice and Short‐Term Clinical Outcomes

Thoracic Cancer, Volume 17, Issue 3, February 2026.
A novel irrigation‐drainage system was developed for fluent intrathoracic hand‐sewn layered anastomosis during robot‐assisted esophagectomy with improved operative efficiency and a satisfied anastomotic field. ABSTRACT Robot‐assisted thoracoscopic surgery facilitates the execution of intrathoracic hand‐sewn layered anastomosis during minimally invasive
Chuan Zhong, Lian Li, Zun Wang, Gu‐Ha A‐Lai, Yong‐Sheng Zhao, Yi‐Dan Lin   +5 more
wiley   +1 more source

Antireflux Surgery for Barrett's Esophagus: Where Do We Stand in Preventing Esophageal Adenocarcinoma?

Annals of the New York Academy of Sciences, Volume 1556, Issue 1, February 2026.
Esophageal adenocarcinoma (EAC) often develops from gastroesophageal reflux disease (GERD), with Barrett's esophagus (BE) as its main precursor. While proton pump inhibitors manage GERD symptoms, their preventive role in EAC remains unclear. This review summarizes advances in diagnosing BE and evaluates anti‐reflux surgery for its potential to prevent ...
Dagmar Kollmann, Cansel Etyemez, Reza Asari, Gerd Jomrich, George Triadafilopoulos, Kenneth J. Vega, Bruno Zilberstein, Margaret J. Zhou, Qin Huang, Hiroshi Mashimo, Eun Ji Shin, John O. Clark, Sebastian F. Schoppmann   +12 more
wiley   +1 more source

Clinicopathologic Characteristics of Barrett's Cancer in Korea

Gut and Liver, 2008
Background/Aims: The incidence of Barrett's cancer is increasing in Western countries, but there have been only a few case reports of this condition in Korea. The aim of this study was to elucidate the endoscopic and pathologic characteristics of Barrett'
doaj   +1 more source

Adenocarcinoma of the esophagogastric junction and its background mucosal pathology: A comparative analysis according to Siewert classification in a Japanese cohort [PDF]

, 2018
Masayuki Urabe, Tetsuo Ushiku, Aya Shinozaki‐Ushiku, Akiko Iwasaki, Sho Yamazawa, Hiroharu Yamashita, Yasuyuki Seto, Masashi Fukayama   +7 more
openalex   +1 more source

Survival Benefit of Neoadjuvant Chemotherapy for Locally Advanced Adenocarcinoma of Esophagogastric Junction

, 2021
Satoshi Suzuki, Shingo Kanaji, Naoki Urakawa, Gosuke Takiguchi, Hiroshi Hasegawa, Yoshiko Matsuda, Kimihiro Yamashita, Takeru Matsuda, Taro Oshikiri, Tetsu Nakamura, Yoshihiro Kakeji   +10 more
openalex   +2 more sources

Short-Term and Long-Term Outcomes Following Transhiatal versus Right Thoracoabdominal Resection of Siewert Type II Adenocarcinoma of the Esophagogastric Junction

Cancer Management and Research, 2020
Jiadi Xing,* Maoxing Liu,* Kai Xu,* Pin Gao, Fei Tan, Zhendan Yao, Nan Zhang, Hong Yang, Chenghai Zhang, Ming Cui, Xiangqian Su Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Gastrointestinal Surgery IV,
Xing J, Liu M, Xu K, Gao P, Tan F, Yao Z, Zhang N, Yang H, Zhang C, Cui M, Su X   +10 more
doaj  

Correlation between methylation of the caveolin‐1 gene and of caveolin‐1 messenger ribonucleic acid, and protein levels and human epidermal growth factor receptor 2 protein expression in adenocarcinomas of the esophagogastric junction [PDF]

, 2019
Ruizhen Liu, Yi Kong, Pengbo Sun, Faliang Li, Xiaopeng Shi   +4 more
openalex   +1 more source

The Impact of Magnetic Sphincter Augmentation (MSA) on Esophagogastric Junction (EGJ) and Esophageal Body Physiology and Manometric Characteristics

, 2021
Shahin Ayazi, Katrin Schwameis, Ping Zheng, Kirsten Newhams, Brittney M. Myers, Andrew D. Grubic, Toshitaka Hoppo, Blair A. Jobe   +7 more
openalex   +1 more source