Results 21 to 30 of about 10,713 (132)

MET Expression in Upper Gastrointestinal Adenocarcinoma: Prevalence, Prognostic Impact, and Implications for Anti‐MET Antibody‐Drug Conjugate Therapy

open access: yesInternational Journal of Cancer, EarlyView.
ABSTRACT MET is an actionable receptor tyrosine kinase, and MET‐directed antibody–drug conjugates (ADCs) have recently entered clinical practice with FDA approval in non‐small cell lung cancer and are now being evaluated across gastrointestinal malignancies, with patient selection based on MET immunohistochemistry (IHC) 3+ membranous staining at ...
Tillmann Bedau   +7 more
wiley   +1 more source

Pregabalin Efficacy in Treatment of Chronic Neurogenic Cough

open access: yesThe Laryngoscope, EarlyView.
The use of neuromodulators for chronic cough has increased; however, the choice of medication, dosing regimen, and duration are still unclear. This longitudinal study of 95 adults taking pregabalin, 75 mg twice daily, for CNC demonstrated 78% improvement or resolution of cough, 17% unchanged, 1% worse cough, with a mean of 6 weeks of therapy, and only ...
Jacqui Allen   +3 more
wiley   +1 more source

Endoscopic Treatment for Esophagogastric Variceal Bleeding in Patients With Acute‐on‐Chronic Liver Failure: An Observational Study

open access: yesPortal Hypertension &Cirrhosis, EarlyView.
In patients with acute‐on‐chronic liver failure (ACLF), esophagogastric variceal bleeding (EGVB) represents a critical complication associated with high short‐term mortality. This study evaluated the efficacy of endoscopic treatment in this specific population and identified prognostic factors associated with 6‐week rebleeding and mortality.
Yanan Sun   +7 more
wiley   +1 more source

Apo10 and TKTL1 as novel liquid biopsy biomarkers for early detection of gastrointestinal malignancies

open access: yesVIEW, EarlyView.
(A) Overview of the study population and schematic illustration showing tumor‐derived apoptotic and metabolic biomarkers, Apo10 and TKTL1, being phagocytosed by circulating monocytes and subsequently detected in peripheral blood. (B) Illustration of the epitope detection in monocytes (EDIM) strategy, using a flow‐cytometric gating approach based on ...
Zhiying Mao   +8 more
wiley   +1 more source

Teratoma at the esophagogastric junction in a neonate

open access: yesIndian Pediatrics, 2015
Teratoma at the esophagogastric junction is extremely rare.A 26-day-old male neonate who presented with vomiting and melena.Investigations revealed a mass at the esophagogastric junction, which was excised and confirmed to be a teratoma.A fistula at the lower end of the esophagus and an esophageal hiatal hernia were observed as complications.A careful ...
Rui, Dong, Chun, Shen, Shan, Zheng
openaire   +2 more sources

Pediatric Esophageal Biomechanics and Remodeling: Integrating Distensibility and Compliance Beyond Luminal Diameter

open access: yesJournal of Gastroenterology and Hepatology, EarlyView.
Esophageal distensibility and compliance provide physiologic information beyond luminal diameter alone in pediatric esophageal disease. This review proposes a practical biomechanics‐informed framework integrating FLIP assessment into interpretation of dysphagia, esophageal remodeling, dilation response, and therapeutic decision‐making in children ...
Brett J. Hoskins   +2 more
wiley   +1 more source

Phase I/II Prospective Study on Endoscopic Ultrasound‐Guided Hepaticogastrostomy as Primary Drainage for Unresectable Malignant Hilar Biliary Obstruction

open access: yesDEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Objectives Various drainage methods have been used for unresectable malignant hilar biliary obstruction (MHBO). However, controlling cholangitis and obstructive jaundice is still challenging. We performed a phase I/II study of endoscopic ultrasound‐guided hepaticogastrostomy (EUS‐HGS) as primary drainage for MHBO.
Tomoki Ogata   +7 more
wiley   +1 more source

Ulcerative Esophagitis With Marked Eosinophilic Infiltration and Fluorodeoxyglucose–Positron Emission Tomography Positivity Requiring Differentiation From Esophagogastric Junction Carcinoma

open access: yesDEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Esophagitis with marked eosinophilic infiltration, including eosinophilic esophagitis (EoE), can rarely present with ulceration or stricture. We report a rare case of positron emission tomography–positive esophagitis with marked eosinophilic infiltration accompanied by ulceration and stricture, requiring differentiation from esophagogastric ...
Yuta Kikuchi   +9 more
wiley   +1 more source

Development and Release of the Munich UICC Staging Tool (MUST): Advancing UICC Staging in Real‐World Data With Insights From Pancreatic and Stomach Cancer

open access: yesInternational Journal of Cancer, Volume 159, Issue 3, Page 757-767, 1 August 2026.
Accurate cancer staging is essential for cancer research and treatment evaluation. However, real‐world data often include incomplete or inconsistent UICC staging classifications. The presented Munich UICC Staging Tool (MUST) automates UICC stage derivation from TNM classifications and tumor characteristics, incorporating novel real‐world data rules to ...
Brigitte Kühnel   +18 more
wiley   +1 more source

Measurement of secondary esophageal motility by Endoluminal Functional Lumen Imaging Probe (EndoFLIP) in young patients with pediatric feeding disorder with and without persistent dysphagia

open access: yes
JPGN Reports, EarlyView.
Gurleen Kaur Kahlon   +6 more
wiley   +1 more source

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