Results 161 to 170 of about 446,222 (404)

Esketamine/Ketamine: Dual‐Action Mechanisms and Clinical Prospects beyond Anesthesia in Psychiatry, Immunology, and Oncology

open access: yesAdvanced Science, EarlyView.
Esketamine and ketamine are widely used for perioperative analgesia and anesthesia. Despite their established roles in analgesia, sedation, and anesthesia, as well as emerging antidepressant, anti‐tumor, and anti‐inflammatory effects, their clinical use is limited due to side effects and addiction potential.
Yinxin Wang   +7 more
wiley   +1 more source

AI‐Guided SERS Defines a Pan‐Cancer Diagnostic Biomarker

open access: yesAdvanced Science, EarlyView.
An AI‐enabled SERS platform integrates automated exosome enrichment with molecular fingerprinting to enable accurate early detection and differential diagnosis of ten common cancers. The system identifies exosomal dATP as a universal Raman biomarker, offering a scalable, noninvasive, and clinically translatable approach for precision oncology ...
Cai Zhang   +15 more
wiley   +1 more source

Cidea Targeting Protects Cochlear Hair Cells and Hearing Function From Drug‐ and Noise‐Induced Damage

open access: yesAdvanced Science, EarlyView.
Acquired sensorineural hearing loss is primarily caused by the damage or loss of cochlear hair cells, induced by factors such as noise exposure and ototoxic drugs. The deficiency of apoptosis‐inducing gene Cidea in Cidea KO mice or by delivering CRISPR/SlugCas9‐HF via AAV to edit Cidea effectively alleviated hair cell damage and hearing loss caused by ...
Shasha Zhang   +14 more
wiley   +1 more source

REVIEW OF PRIMARY MULTIPLE CANCERS COMBINED IN THE ESOPHAGUS AND OTHER ORGAN

open access: bronze, 1994
Kenichiro BABA   +8 more
openalex   +2 more sources

Combined chemotherapy and radiotherapy compared with radiotherapy alone in patients with cancer of the esophagus.

open access: yesNew England Journal of Medicine, 1992
A. Herskovic   +9 more
semanticscholar   +1 more source

Thermally Gated Dual‐Cascade Nanozyme for Enhanced Mild‐Temperature Photothermal Therapy

open access: yesAdvanced Science, EarlyView.
A thermo‐responsive cascade nanozyme (Ru‐GOx‐PNN) synergistically enhances mild photothermal therapy by dual suppression of HSP70 through ROS‐induced lipid peroxidation and ATP depletion. This intelligent system effectively overcomes thermotolerance and amplifies apoptosis, offering a safe and precise strategy for tumor treatment.
Shuyu Wang   +7 more
wiley   +1 more source

A CASE OF ACQUIRED ESOPHAGO-BRONCHIAL FISTULA CAUSED BY A PERFORATION OF DIVERTICULUM OF UPPER PORTION OF THE ESOPHAGUS

open access: bronze, 1990
Shoji Sakai   +6 more
openalex   +2 more sources

The Influence of Age, Smoking, Antiretroviral Therapy, and Esophagitis on the Local Immunity of the Esophagus in Patients with AIDS [PDF]

open access: gold, 2013
Camila Lourencini Cavellani   +8 more
openalex   +1 more source

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