Engineering antibodies with cancer‐associated binding sites
This review describes antibodies that perform direct/indirect roles in cancer treatment by binding to effective targets and discusses how antibodies kill tumors and modulate tumor microenvironment through these targets. The classification of expression systems for antibody production is summarized to guide appropriate selection based on different ...
Yinqi Tian+4 more
wiley +1 more source
Primary extraskeletal osteosarcoma of the esophagus with PPM1D-BCAS3 fusion: a case report and literature review. [PDF]
Luo S, Tian X, Xu T, Ji Q, Li Y, Wang J.
europepmc +1 more source
Introducing Novel Surgical Clinical Correlations Into an Undergraduate Medical Anatomy Course
ABSTRACT Anatomy education is a hallmark of many preclinical medical school curricula, but students are often unable to identify the clinical relevance of anatomy and its applications. Vertical curricula that integrate clinical concepts into the preclinical basic science years and vice versa have been shown to benefit student learning and increase ...
Liam McLoughlin+5 more
wiley +1 more source
Shallow endoscopic submucosal dissection using a gas-free immersion system to prevent strictures after esophageal dissections. [PDF]
Nomura T+6 more
europepmc +1 more source
The Myofascial Continuum: Anatomical Insights Into Noncardiac Chest Pain
ABSTRACT Angina, commonly known as chest pain, is the primary symptom of ischemic heart disease and can also present as pain in the neck, shoulder, jaw, arm, or back. Noncardiac chest pain (NCCP) is a common disorder with various causes, marked by recurrent chest pain that mimics ischemic heart pain.
Prabu Raja G+3 more
wiley +1 more source
Advanced Endoscopic Management of a Full-Thickness Esophageal Perforation From Food Impaction: A Case of Successful Stent-Assisted Healing. [PDF]
Bin Hameed U+4 more
europepmc +1 more source
Abstract Background Overweight and obesity are known risk factors for cancer. The aim of this study was to investigate associations of body mass index (BMI) and waist circumference (WC) with incidence of 27 site‐specific cancers stratified by sex and menopausal status accounting for non‐linearity.
Seonghye Kim+7 more
wiley +1 more source
Tacrolimus-Induced Acute Esophageal Necrosis Postorthotopic Liver Transplantation. [PDF]
Tang W+9 more
europepmc +1 more source
Ubiquitination in cancer: mechanisms and therapeutic opportunities
Abstract Ubiquitination, a key post‐translational modification, plays an essential role in tumor biology by regulating fundamental cellular processes, such as metabolism and cell death. Additionally, it interacts with other post‐translational modifications, which are closely linked to tumorigenesis, tumor progression, the tumor microenvironment, and ...
Susi Zhu+7 more
wiley +1 more source