Results 101 to 110 of about 180,731 (257)

An Injectable Metal‐Drug Supramolecular Condensate Enables Radiosensitization and Systemic Antitumor Immunity for Post‐Surgical Osteosarcoma Therapy

open access: yesAdvanced Science, EarlyView.
This work designed an injectable metal‐drug supramolecular condensate formed from hafnium ions and alendronate (Hf‐ALN) and loaded with the COX‐2 inhibitor celecoxib (CXB) for synergistic radioimmunotherapy of postoperative osteosarcoma. Mechanistically, upon X‐ray irradiation, Hf enhances radiation energy deposition, ROS generation, and DNA damage ...
Tianhua Xiao   +12 more
wiley   +1 more source

Mitochondria‐Targeted Multimodal Nanotherapeutics Suppress Oxidized mtDNA‐Driven Inflammation at the Source

open access: yesAdvanced Science, EarlyView.
Ox‐mtDNA fragments escaping from mitochondria drive robust inflammatory responses. A targeted nanoplatform simultaneously inhibits mitochondrial FEN1‐mediated mtDNA cleavage and scavenges ROS, preventing the generation of immunogenic Ox‐mtDNA fragments. The released SeNPs further promote autophagic clearance of cytosolic mtDNA. Consequently, cGAS‐STING,
Wen‐Ling Li   +7 more
wiley   +1 more source

Chapter 7 In-Situ Electrochemical ESR

open access: yes, 1989
This chapter discusses In-Situ Electrochemical electron spin resonance spectroscopy (ESR). The existence of radicals as intermediates in a great variety of electrode reactions is well established.
Andrew M. Waller, Richard G. Compton
core   +1 more source

Ultrasound‐Activated Nanoinhibitors Blocking the Chemo‐Immune Checkpoint to Overcome Chemotherapy‐Induced Immune Resistance

open access: yesAdvanced Science, EarlyView.
A sono‐responsive chemo‐immune checkpoint nanoinhibitor (Sono‐TT8) co‐delivering TPZ chemotherapy and siXkr8 simultaneously kills tumor cells and blocks PS externalization, reversing chemotherapy‐induced immunosuppression and enhancing antitumor immunity. ABSTRACT Breast cancer features an immunosuppressive tumor microenvironment following chemotherapy
Yunfan Liu   +13 more
wiley   +1 more source

Electrical Conductivity and ESR Studies of Carbon-Black-Loaded Natural Rubber

open access: yes, 1988
The results of electrical conductivity and electron spin resonance (ESR) measurements on NR with four types of carbon black filler were reported. Two forms of space change limited current (SCLC) were identified, indicative of different electron trap ...
Bo, Na Peng   +9 more
core   +1 more source

ROS‐Responsive Nanoparticle Delivery of Dexmedetomidine Protects the Gut Vascular Barrier After Intestinal Ischemia/Reperfusion via the HDAC‐H3K27ac‐TCF4 Axis

open access: yesAdvanced Science, EarlyView.
A low dose of dexmedetomidine, delivered by ROS‐responsive nanoparticles, preferentially accumulates in the ischemic intestine and restores gut vascular barrier integrity after ischemia/reperfusion injury. This nanoparticle‐based strategy prevents bacterial translocation and liver damage without cardiorespiratory side effects, working through HDAC ...
Hu‐Fei Zhang   +10 more
wiley   +1 more source

Influence of Steel Melting Processes on Tensile Properties of 14Cr-15Ni-Ti Stainless Steel

open access: yesHigh Temperature Materials and Processes, 2011
A titanium-modified 14Cr-15Ni-2Mo austenitic stainless steel, known as alloy D9, has been chosen as the material for the fuel cladding and hexagonal wrapper of the Prototype Fast Breeder Reactor presently under construction at Kalpakkam.
Nandagopal M.   +4 more
doaj   +1 more source

Water‐Soluble Luminescent Trityl Radical for Fluorescence/Magnetic Resonance Dual‐Modal Imaging Probe

open access: yesAdvanced Science, EarlyView.
Stable water‐soluble luminescent tris(2,4,6‐trichlorophenyl)methyl (TTM) radicals, TTM‐trisTP3B and TTM‐trisTP9B, were designed and successfully synthesized. They exhibited deep‐red emissions and high photostability in water. TTM‐trisTP3B exhibited dual functionality as a fluorescence imaging (FI) probe and a magnetic resonance imaging (MRI) contrast ...
Kosuke Anraku   +6 more
wiley   +1 more source

ESR imaging of pyrolytic carbon films

open access: yes, 2004
Since electron spin resonance (ESR) is a sensitive tool for the characterisation of microstructures of pyrolytic carbon, we applied spatially resolved ESR for detecting the homogeneity of the gas phase reactions required for chemical vapour deposition ...
M. Drescher, E. Dormann
core   +1 more source

Self‐Sustaining Sensing Systems: Integration Strategies and Signal–Power Matching in Energy‐Harvesting Electronics

open access: yesAdvanced Science, EarlyView.
Energy‐harvesting‐integrated sensors couple ambient energy conversion with sensing, processing, and wireless communication. This review organizes recent progress through integration architectures and operating principles, revisiting co‐packaged, monolithic, and co‐functional designs together with always‐on, event‐driven, and multi‐modal sensing modes ...
Taehyun Park   +5 more
wiley   +1 more source

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