Results 91 to 100 of about 2,280 (257)

Threshold-oriented ecosystem-service relationships from interpretable machine learning to spatial management: A case from Shandong Province, China

open access: yesEcological Indicators
Ecosystem-service relationships (ESRs) – the synergies and trade-offs that arise when multiple services respond to the same biophysical and human drivers – are decision-relevant outcomes, but most existing studies have treated them only indirectly and ...
Qiran Ren, Dandan Liu, Weifen Lin
doaj   +1 more source

Magneto‐NIR‐II‐Programmed Cascade Nanozymes Unlocking Blood–Brain Barrier Translocation and Autophagic Resistance in Glioblastoma

open access: yesAdvanced Science, EarlyView.
Magneto‐NIR‐II‐programmed NFSH nanozymes integrate magnetic blood–brain barrier (BBB) translocation, CD44 targeting, multimodal imaging, and cascade catalytic therapy for glioblastoma. Alternating magnetic fields and NIR‐II irradiation amplify ferroptosis, release H2S, suppress autophagic and mitophagic repair, and reshape the immune microenvironment ...
Ruocan Liu   +7 more
wiley   +1 more source

A pH‐Switchable Cerium Single‐Atom Enzyme for Peri‐Implantitis Therapy via JAK‐STAT Signaling Axis‐Mediated Macrophage Reprogramming

open access: yesAdvanced Science, EarlyView.
A pH‐switchable cerium single‐atom enzyme is developed for stage‐specific peri‐implantitis therapy. Acidic conditions trigger antibacterial peroxidase‐like activity, whereas neutral conditions activate an antioxidant superoxide dismutase ‐ and catalase ‐like enzymatic relay. This microenvironment‐adaptive catalytic strategy suppresses the IL‐6/JAK‐STAT
Xiaomin Xia   +10 more
wiley   +1 more source

Functional Sex Reversal in Adult Gonochoristic Teleosts is Mediated by Ovarian Germline Stem Cell Plasticity and Somatic Cell Transdifferentiation

open access: yesAdvanced Science, EarlyView.
Oocytes play crucial roles in maintaining ovarian fate in adult gonochoristic fish. Targeted oocyte ablation with aromatase inhibition triggers the activation of surviving germline stem cells and the transdifferentiation of somatic cells from granoulosa/theca to Sertoli/Leydig lineages, inducing a complete and functional female‐to‐male sex reversal ...
Yang Yang   +6 more
wiley   +1 more source

ESR Essentials

open access: yesEuropean Radiology
MRI-based T-staging in prostate cancer enables more precise and individualised treatment decisions compared with traditional clinical T-staging, yet inconsistent image acquisition, interpretation, and terminology limit reproducibility and clinical integration.
Agrotis, Georgios   +10 more
openaire   +4 more sources

An Avalanche Effect Nanomodulator Triggers Cascade Ferroptosis/Cuproptosis for Immunosuppressive Microenvironment Remodeling

open access: yesAdvanced Science, EarlyView.
A nanomodulator called L‐Arginine/lificiguat@Copper‐hollow Prussian blue@Calcium phosphate nanoparticles is constructed to launch a self‐amplifying “avalanche effect” in tumor cells. The ensuing cascade, triggered by the acidic tumor microenvironment and near‐infrared light, induces calcium overload, generates a reactive oxygen species and reactive ...
Hongmei Zhou   +9 more
wiley   +1 more source

Toward Social Disclosure Alignment: Evaluating the Interoperability of ISSB S2 with ESRS and GRI Standards

open access: yesSocieties
The evolution of sustainability reporting has led to an increased emphasis on environmental disclosures, often at the expense of social and governance dimensions.
Péter Molnár   +2 more
doaj   +1 more source

Computationally Evidence‐Grounded Sequence‐First Design of Peptide Binders

open access: yesAdvanced Science, EarlyView.
BOND‐PEP enables controllable, sequence‐first peptide binder design by grounding generation in binding evidence retrieved for each target. It uses topology‐conditioned message passing to integrate relevant peptide examples with the target protein sequence, forming a residue‐level representation that guides the generation of diverse, target‐specific ...
Wenze Ding
wiley   +1 more source

Photocatalytic Recovery of Aromatic Chemicals from Waste Plastics

open access: yesAdvanced Science, EarlyView.
This Review summarizes recent advances in the photocatalytic recovery of aromatic chemicals from plastic waste, with emphasis on fundamental mechanism, representative catalytic systems, and future challenges and development directions, which is expected to provide in‐depth and valuable insights and references into the key role of sustainable catalysis ...
Lizhen Liu, Jutarat Jitrada, Jun Huang
wiley   +1 more source

Categorisation of SDG targets into ESG pillars based on ESRS taxonomy

open access: yesDiscover Sustainability
This study examines the alignment between the Sustainable Development Goals (SDGs) and the Environmental, Social, and Governance (ESG) pillars through the lens of the European Sustainability Reporting Standards (ESRS) taxonomy, complemented by the Global
Bence Lukács   +2 more
doaj   +1 more source

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