Results 71 to 80 of about 3,947 (298)

Targeting Golgi–STING Signaling to Reprogram Innate and Adaptive Immunity for the Treatment of Implant‐Associated Infections

Advanced Science, EarlyView.
This study presents an ultrasound‐responsive nanoplatform, CS‐BT@MZ@NEs, with a BaTiO3/Mn‐Zif‐8 core and a chondroitin sulfate coating for Golgi targeting. By leveraging neutrophil hitchhiking, it enables targeted delivery to infection sites. Under ultrasound stimulation, CS‐BT@MZ@NEs generates ROS and modulates Golgi pH to activate cGAS–STING ...
Shicheng Huo, Naifeng Zhu, Zhuocheng Lyu, Yifei Liu, Zhenjiang Xu, Chun Zhou, Yaochao Zhao, Changgui Shi   +7 more
wiley   +1 more source

Amplification of Endoplasmic Reticulum Stress via Inhibiting Lipid Droplet Formation to Enhance Chemodynamic Immunotherapy

Advanced Science, EarlyView.
An endoplasmic reticulum (ER)‐targeted chemodynamic nanoagent (TCBQ/iLD‐ER NPs) comprising •OH‐generating tetrachloro‐1,4‐benzoquinone (TCBQ) and lipid droplets (LDs) formation inhibitor (iLD) is developed for chemodynamic immunotherapy of tumors. After ingestion by cancer cells, TCBQ/iLD‐ER NPs preferentially accumulate in the ER and react with ER ...
Huilan Cai, Shaoru Zhuang, Yang Zhu, Rujiang Ao, Meili Yu, Tingting Cui, Jun Wang, Xuegang Niu, Hongwei Huang, Shanshan Peng, Yu He, Lisen Lin, Huanghao Yang   +12 more
wiley   +1 more source

Діагностика рівня імплементації цінностей сталого розвитку в практику українських підприємств

Journal of Innovations and Sustainability
Мета. Метою роботи є обґрунтування й апробація кількісно орієнтованої діагностичної рамки оцінювання рівня імплементації цінностей сталого розвитку (ESG) в практику українських підприємств у 2021–2025 рр.
Oleh Knіaz, Rostyslav Slaviuk
doaj   +1 more source

ESRS som katalysator for bærekraftige forretningsmodeller [PDF]

Denne masteravhandlingen har utforsket hvordan selskaper tilpasser seg og håndterer CSRD gjennom kravene til rapportering i ESRS. Studien ser på hvordan, og om, ESRS fungerer som en katalysator for utviklingen av mer bærekraftige forretningsmodeller.
Angell-Petersen, Helge Mikael
core  

Asymmetrically Coordinated Dual‐Atom Manganese Contrast Agents Enabling High‐Efficiency T1 Enhanced MRI for Precise Tumor Visualization

Advanced Science, EarlyView.
A novel dual‐atom manganese MRI contrast agent (Mn‐BN) with a unique asymmetric coordination geometry provided a promising platform for sensitive and specific tumor imaging. In mice model, Mn‐BN nanoparticles precisely functioned as both a primary tumor‐specific enhancer in subcutaneous models and a hepatocyte‐specific agent in liver metastases models ...
Ding Yang, Qing‐Yang Li, Jianli Liang, Gengyou Li, Nan Sun, Qianqian Song, Haitao Zhu, Xiaoting Li, Zechuan Li, Jiankai Dong, Weisheng Guo, Yafang Xiao, Chun‐Sing Lee, Ying‐Shi Sun   +13 more
wiley   +1 more source

Maintaining Integrity Under Stress: Envelope Stress Response Regulation of Pathogenesis in Gram-Negative Bacteria

Frontiers in Cellular and Infection Microbiology, 2019
The Gram-negative bacterial envelope is an essential interface between the intracellular and harsh extracellular environment. Envelope stress responses (ESRs) are crucial to the maintenance of this barrier and function to detect and respond to ...
Claire L. Hews, Timothy Cho, Gary Rowley, Tracy L. Raivio   +3 more
doaj   +1 more source

CSRD-direktiivin tuomat muutokset Musti Groupin kestävyysraportointiin : standardit ESRS E1 ja ESRS S1 [PDF]

Euroopan Unionin uusi kestävyysraportointidirektiivi CSRD (Corporate Sustainability Reporting Directive) tuli voimaan vuonna 2023, mikä velvoittaa ensimmäisenä suuria yrityksiä raportoimaan uusien standardien mukaisesti vuoden 2024 tilikaudesta.
Kulmala, Veera
core  

Supramolecular Assembly of Stepped‐Persistent ROS Nanogenerator for Sustained Tumor Immunotherapy

Advanced Science, EarlyView.
ROS catalytic systems often fail to achieve both effective tumor elimination and persistent immune activation due to their monotonous ROS production profiles. A stepped‐persistent ROS nanogenerator was developed by supramolecularly assembling multiple ROS generation modules within a nanofiber structure to simultaneously extend ROS generation duration ...
Zhenqiang Wang, Ming Qin, Wenjing Lai, Shiwen Chen, Fengling Wang, Dandan Xie, Maohua Chen, Changpeng Hu, Kui Wang, Rong Zhang, Guobing Li   +10 more
wiley   +1 more source

The Narrative Component of Corporate Sustainability Reporting under the CSRD Implementation

Проблеми сучасних трансформацій. Серія: економіка та управління
The transformation of corporate reporting towards mandatory ESG disclosure is accompanied by a rapid increase in the role of the narrative component as a key means of communication between a companies and their stakeholders.
Олена Тивончук, Дмитро Тітов   +1 more
doaj   +1 more source

A High‐Entropy Strategy for Chemoresistive Ethanol Sensors With Remarkably Rapid and Selective Response

Advanced Science, EarlyView.
The configurational‐entropy strategy enables rapid and sensitive ethanol detection using a multicomponent oxide. The high‐entropy (InSnFeZnW)Ox provides enriched oxygen vacancies and diverse adsorption sites that strengthen surface reactivity. The sensor achieves a 5135% ethanol response with fast kinetics and stable long‐term operation.
Gi Baek Nam, Jin Ho Seo, Youngmin Kim, Hyuk Jin Kim, Yeong Jae Kim, Seon Ju Park, YunKyung Kim, Hyeon‐Min Yu, Jiwoo Lee, Ji Hyeon Lim, Jiheon Lim, Jong Hun Kang, WooChul Jung, Jong Jin Jung, Jeong Woo Han, Seung Eon Moon, Seong Ju Hwang, Jong‐Hoon Kang, Zhigang Zhu, Ho Won Jang   +19 more
wiley   +1 more source