Results 41 to 50 of about 6,152 (282)

From the Poetry of Late Socialism to the Dogmatism of Democracy: The Cinema of the Former Eastern Bloc before and after the Collapse of Communism [PDF]

open access: yes, 2020
Using the examples of two films from the late socialist era, Roman Balayan’s Flights in Dream and Reality (1982) and Mircea Daneliuc’s Glissando (1982) and following Alexei Yurchak’s description of vnye as “deterritorialized milieus,” I plan to show how ...
Tion, Lucian
core  

Survivin and Aurora Kinase A control cell fate decisions during mitosis

open access: yesMolecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir   +2 more
wiley   +1 more source

System Error: Complicity with Surveillance in Contemporary Workplace Documentaries [PDF]

open access: yes, 2016
This article sets itself against the bulk of scholarship on surveillance, which is characterized by emphasis either on Michel Foucault’s analysis of the Panopticon, or on Gilles Deleuze’s too-brief “Postscript on the Societies of Control.” In contrast to
Ring, A
core   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Essay Film as a Dialogical Form

open access: yesJOMEC Journal, 2019
The essay film is one emerging genre in which the sonic elements and the editing characteristics are constructing the basis of its communication structure within and beyond the audiovisual material. This paper will enlighten the unique language and the means of communication of the essay form.
openaire   +2 more sources

Adorno?s Grey, Taussig?s Blue: Colour, Organization and Critical Affect [PDF]

open access: yes, 2017
In this article we seek to open up the study of affect and organization to colour. Often simply taken for granted in organizational life and usually neglected in organizational thought, colour is an affective force by default.
Adorno T. W.   +44 more
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

The Animation of Cinema

open access: yesSemiotic Review
This essay (originally published in THE SEMIOTIC REVIEW OF BOOKS VOLUME 18.2 2008, republished here with permission) seeks to resurrect the name, work and extraordinary achievements of the most significant pioneering film animator at best marginalized ...
Alan Cholodenko
doaj   +1 more source

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