Results 101 to 110 of about 504,510 (309)

Kritikou k nepojmovému. O Adornově esejistické metodě

Filosofický časopis
The goal that the author of this study focuses on is to provide a brief introduction to the issue of language in the work of Theodor W. Adorno and, in this context, to interpret his approach to philosophy through a presentation of his essayistic form ...
Dyčková, Alžběta
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Essays in Macroeconomics

Essais en macroéconomie Cette thèse présente trois essais indépendants en macroéconomie. Le Chapitre 1, co-écrit avec Alexandre Gaillard, étudie les implications macroéconomiques des politiques de stabilisation lorsque l’inégalité, les cycles économiques et la croissance technologique à long terme interagissent.
openaire   +3 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

The audiovisual essay as performative research

, 2016
Editorial introduction to the Audiovisual Essay section of NECSUS: European Journal of Media Studies, Autumn ...
Grant, Catherine
core  

Participant 017 Community Conversations Essay

, 2020
In this essay, Participant 17 shares their experience working in a hospital as a patient care technician. The participant shares sadness and painful experiences of witnessing the loss of many lives during the COVID-19 pandemic.
Sara
core  

Anselm Jappe (2020): Béton, arme de construction massive du capitalisme. Montreuil: l’Échappée

Digithum
Review of Béton, arme de construction massive du capitalisme, by Anselm Jappe, published in 2020.
Gloria Guirao Soro
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

ESSAY FILM NOW!

Public Lecture organised by the Arts Foundation and hosted by the Whitechape Gallery, London on the definition of the Essay Film ...
Stevens, S.
core