Results 41 to 50 of about 270,172 (262)

12 Angry Men (1957)

2i Revista de Estudos de Identidade e Intermedialidade, 2022
This essay focuses on the imagetic power of the word as a central element of the film 12 Angry Men (1957), directed by Sidney Lumet, with a screenplay by Reginald Rose from his writings and TV special (CBS, 1954, directed by Franklin Schaffner).
Helciclever Barros da Silva Sales
doaj   +1 more source

Learning Film Magic from the Professionals: The Film Studio as a Tourist Destination [PDF]

, 2015
The phenomenon of film tourism is about as old as the movies themselves. Many consumers have been inspired by their favourite films to travel either to the locations they have seen on screen or to the locations where they have been filmed.
Wohlfeil, Markus
core   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

The The Work of Art as a Fictionalized Duplicate of Life: Boris Lehman's Babel film project in the Light of Marcel Proust's In Search of Lost Time

Arte, Individuo y Sociedad
Belgian filmmaker Boris Lehman has created what is surely the most ambitious film diary in the history of cinema, Babel, a twenty-four-hour film divided into nine parts and several appendices, which traces a sort of sublimated filmic duplicate of the ...
Guillermo G. Peydró
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

The Essay Film and Space: The Essayistic Filmic Space as aLocation of Thought [PDF]

, 2014
This practice-led research investigates the function of filmic space in essayistic discourse through the dialogic relationship between the essay film My Pink City that reflects on post-Soviet urban space in Yerevan and a written thesis that examines the ...
Gegisian, A., Gegisian, A.
core  

Josef Fares’ Zozo as accented cinema [PDF]

, 2016
In 2005, the Lebanese-Swedish filmmaker Josef Fares, who had attained recognition in Sweden through the immigrant comedies Jalla! Jalla! (2000) and Kopps (2003), presented his third feature film and first drama, Zozo, inspired by Fares’s own migration to
Alexander, Elizabeth Lindsay
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

PEMBELAJARAN MEMPRODUKSI TEKS ULASAN FILM BERORIENTASI PADA PERWATAKAN TOKOH DENGAN MENGGUNAKAN TEKNIK DYADIC ESSAY PADA SISWA KELAS XI SMAN 12 BANDUNG TAHUN PELAJARAN 2015/2016 [PDF]

, 2016
Memproduksi dalam Kurikulum 2013 merupakan keterampilan menulis. Me-nulis merupakan suatu keterampilan berbahasa yang dipergunakan untuk berkomu-nikasi secara tidak langsung.
NOVI KARTIANI, 125030048
core  

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source