Results 131 to 140 of about 1,949,102 (353)

Review of medicine registration system in Tanzania [PDF]

open access: yes, 2019
>Magister Scientiae - MScRegistration of medicines is an essential function of the national medicine regulatory system of any country. Since the start of the medicine registration system in Tanzania in early 2000s, no systematic review has been carried
Kisoma, Sunday Ally
core   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Malaria case management: Enabling appropriate use of ACTs

open access: yesInternational Journal of Infectious Diseases, 2014
E.N. Wesangula   +3 more
doaj   +1 more source

Babesia divergens egress from host cells is orchestrated by essential and druggable kinases and proteases [PDF]

open access: gold, 2023
Brendan Elsworth   +11 more
openalex   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

In-silico evaluation of Malawi essential medicines and reactive metabolites for potential drug-induced toxicities [PDF]

open access: gold, 2021
Ibrahim Chikowe   +3 more
openalex   +1 more source

THE CONTRIBUTION OF NORTH DAKOTA'S COMMUNITY PHARMACIES TO THE STATE'S ECONOMY [PDF]

open access: yes
A pharmacist shortage, mail and internet competition, thinning margins, and third-party payer issues are some of the issues challenging community pharmacies.
Hodur, Nancy M., Leistritz, F. Larry
core   +1 more source

Ketersediaan dan Peresepan Obat Generik dan Obat Esensial di Fasilitas Pelayanan Kefarmasian di 10 Kabupaten/kota di Indonesia [PDF]

open access: yes, 2010
Background: The Ministry of Health has a special guidance for increasing the utilization of generic drugs in governmental health facilities. Beside, The Ministry of Health also has regulation for writing a generic drugs prescription at governmental ...
Handayani, R. S. (Rini)   +3 more
core  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

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