Results 131 to 140 of about 4,958,090 (306)
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Action Programme on Essential Drugs : progress report 1996, interim report of the biennium 1996-1997
, 1997 ONLINEDAP/MAC(9)/97.542 ...
WHO Action Programme on Essential Drugs
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Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
Action Programme on Essential Drugs : interim report of the biennium 1998-1999 : February 1999
, 1999 WHO/HTP/EDM/MAC(11)/99.462 ...
WHO Action Programme on Essential Drugs
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FEBS Letters, EarlyView.Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
Quality of Ayurvedic health care delivery in provinces of India: Lessons from essential drugs availability at State run Ayurveda dispensaries. [PDF]
J Ayurveda Integr Med, 2018 Rastogi S.
europepmc +1 more source
RNA‐related functions of BRCA2 in transcription, replication, and genome stability
FEBS Letters, EarlyView.Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda +2 more
wiley +1 more source
National Drugs Advisory Board annual report 1975
, 1975 By the end of 1975. the National Drugs Advisory Board had 15 months of experience in the management of mandatory licensing systems for medicinal products and for manufacturers of pharmaceuticals in Ireland. With few exceptions.
National Drugs Advisory Board (NDAB)
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Reports of side effects associated with the use of drugs 1982 [PDF]
, 1982 The National Drugs Advisory Board received 540 reports during 1982 from which 1051 side-effects were reported. 39% of the reactions received occurred in association with drugs affecting the central nervous system, over half concerned analgesics, 18% of
National Drugs Advisory Board (NDAB)
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Analysis of essential drugs lists of a regional healthcare coordination center in Rio Grande do Sul
O Mundo da Saúde, 2018 In Brazil municipalities are responsible for initiating the guarantee of access to essential medicines by selecting those that will be included in their lists. This study aimed to analyze how the Municipal Lists of Essential Medicines (MLEM) are prepared,
Mariele Salvi +3 more
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