PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
A DOSE OF YOUR OWN MEDICINE? DRUG TESTING ON CHILDREN AND LABELING DRUGS FOR PEDIATRIC USE--ESSENTIAL NEEDS [PDF]
Children are not just miniature adults; a child metabolizes and absorbs drugs differently than adults, making drug testing and labeling regarding pediatric use essential. This paper first addresses these needs in more detail.
Gendell, Stephanie J.
core
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
Drug Management Reviews in District Drug Management Unit and General Hospital [PDF]
Drug is one of the essential elements in healthcare that should be effectively and efficiently managed. Following the decentralization in 2001 in Indonesia, drug management has changed in district drug management units and also in District General ...
Handayani, R. S. (Rini) +2 more
core
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
Quality of Ayurvedic health care delivery in provinces of India: Lessons from essential drugs availability at State run Ayurveda dispensaries. [PDF]
Rastogi S.
europepmc +1 more source
Unbiased functional genetic screens reveal essential RNA modifications in human cancer and drug resistance [PDF]
Cornelius Pauli +25 more
openalex +1 more source
Survey on Sustainable Mechanisms for Financing Essential Drugs at Loumbila in Burkina Faso [PDF]
Hamado Saouadogo
openalex +1 more source
The Dutch list of essential drugs for undergraduate medical education: A modified Delphi study [PDF]
Erik M. Donker +14 more
openalex +1 more source
Essential Drugs – Whose Responsibility? [PDF]
openaire +2 more sources

