Results 151 to 160 of about 1,949,102 (353)

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

A DOSE OF YOUR OWN MEDICINE? DRUG TESTING ON CHILDREN AND LABELING DRUGS FOR PEDIATRIC USE--ESSENTIAL NEEDS [PDF]

open access: yes, 2012
Children are not just miniature adults; a child metabolizes and absorbs drugs differently than adults, making drug testing and labeling regarding pediatric use essential. This paper first addresses these needs in more detail.
Gendell, Stephanie J.
core  

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Drug Management Reviews in District Drug Management Unit and General Hospital [PDF]

open access: yes, 2009
Drug is one of the essential elements in healthcare that should be effectively and efficiently managed. Following the decentralization in 2001 in Indonesia, drug management has changed in district drug management units and also in District General ...
Handayani, R. S. (Rini)   +2 more
core  

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

Unbiased functional genetic screens reveal essential RNA modifications in human cancer and drug resistance [PDF]

open access: gold
Cornelius Pauli   +25 more
openalex   +1 more source

The Dutch list of essential drugs for undergraduate medical education: A modified Delphi study [PDF]

open access: bronze, 2022
Erik M. Donker   +14 more
openalex   +1 more source

Home - About - Disclaimer - Privacy