Results 131 to 140 of about 944,359 (264)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Relationships between flavonoids and selected elements in infusions of medicinal herbs

Open Chemistry, 2014
Konieczynski Pawel, Arceusz Agnieszka, Wesolowski Marek   +2 more
doaj   +1 more source

Exposure and Health Impact Assessment of Essential and Non-essential Elements in Rice Sold on Ghanaian Markets. [PDF]

Environ Health Insights
Awewomom J, Arhin TY, Takyi YD, Gyasi Yaw A, Saaka J, Opoku F, Tandoh MA, Amankwah EA, Akoto O.   +8 more
europepmc   +1 more source

Association between gestational levels of toxic metals and essential elements and cerebral palsy in children. [PDF]

Front Neurol, 2023
Weyde KVF, Winterton A, Surén P, Andersen GL, Vik T, Biele G, Knutsen HK, Thomsen C, Meltzer HM, Skogheim TS, Engel SM, Aase H, Villanger GD.   +12 more
europepmc   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Commentary: Essential elements that contribute to the recovery of persons with severe mental illness: a systematic scoping study. [PDF]

Front Psychiatry
Muramatsu H.
europepmc   +1 more source

Publisher Correction: Essential elements of radical pair magnetosensitivity in Drosophila. [PDF]

Nature, 2023
Bradlaugh AA, Fedele G, Munro AL, Hansen CN, Hares JM, Patel S, Kyriacou CP, Jones AR, Rosato E, Baines RA.   +9 more
europepmc   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Essential Elements (Fe, Cu, Mn, Zn) in Meconium, and Newborn Length and Weight, in Relation to Maternal Lifestyle and Diet. [PDF]

Nutrients
Mimica B, Pribisalic A, Knezovic Z, Sutlovic D.   +3 more
europepmc   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source