Results 121 to 130 of about 4,393,589 (384)

Gasotransmitters in Modern Medicine: Promises and Challenges in the Use of Porous Crystalline Carriers

open access: yesAdvanced Healthcare Materials, EarlyView.
This perspective provides an overview of the growing interest in utilizing various gasotransmitters—small gaseous signaling molecules namely nitric oxide (NO), carbon monoxide (CO), and hydrogen sulfide (H2S)—for several therapeutic applications, with emphasis on the potential use of porous materials as carriers to provide safe and controlled local ...
Rosana V. Pinto   +2 more
wiley   +1 more source

Investigation of Homocysteine-Pathway-Related Variants in Essential Hypertension

open access: yesInternational Journal of Hypertension, 2012
Hyperhomocysteinemia (hHcy) has been associated with an increased risk of cardiovascular disease and stroke. Essential hypertension (EH), a polygenic condition, has also been associated with increased risk of cardiovascular related disorders.
Javed Y. Fowdar   +4 more
doaj   +1 more source

Effect of allopurinol on blood pressure of adolescents with newly diagnosed essential hypertension: a randomized trial.

open access: yesJournal of the American Medical Association (JAMA), 2008
CONTEXT Hyperuricemia is a predictor for the development of hypertension and is commonly present in new-onset essential hypertension. Experimentally increasing uric acid levels using a uricase inhibitor causes systemic hypertension in animal models ...
D. Feig   +2 more
semanticscholar   +1 more source

The genetics of cardiovascular disease [PDF]

open access: yes, 2008
Recent advances in genotyping technology and insights into disease mechanisms have increased interest in the genetics of cardiovascular disease. Several candidate genes involved in cardiovascular diseases were identified from studies using animal models,
Abu-Amero   +72 more
core   +1 more source

Advanced Multipurpose Spectroscopic Nanobio‐Device for Concurrent Lab‐on‐a‐Chip Label‐Free Separation and Detection of Extracellular Vesicles as Key‐Biomarkers for Point‐of‐Care Cardiovascular Disease Diagnostics

open access: yesAdvanced Healthcare Materials, EarlyView.
AIMSPec‐LoC is a novel lab‐on‐a‐chip platform integrating size‐based extracellular vesicle (EVs) separation with label‐free Raman spectroscopy and AI‐powered classification via SKiNET. This high‐throughput, portable system enables real‐time, multiplexed molecular fingerprinting of EVs from biofluids, offering transformative potential for early, non ...
Emma Buchan   +3 more
wiley   +1 more source

Urinary Kallikrein in normotensive Subjects and in Patients with Essential Hypertension [PDF]

open access: yes, 1980
Distler, A.   +7 more
core   +4 more sources

Hubungan antara Homosistein dan Nitrit Oksid pada Hipertensi Esensial di Jawa Tengah, Indonesia [PDF]

open access: yes, 2007
Background: The essential hypertension has been related to endothelium-dependent vasodilatation disorders that result of decreasing of nitric oxide (NO) bioavailability.
Ahmad Husain Asdie, Mohammad Hakimi, Abdul Salam M Sofro, Sunarti
core  

Aging on Chip: Harnessing the Potential of Microfluidic Technologies in Aging and Rejuvenation Research

open access: yesAdvanced Healthcare Materials, EarlyView.
This review highlights recent advances in microfluidic technologies for modeling human aging and age‐related diseases. It explores how organ‐on‐chip platforms improve physiological relevance, enable rejuvenation strategies, facilitate drug screening, detect senescent cells, and identify biomarkers.
Limor Zwi‐Dantsis   +5 more
wiley   +1 more source

MTHFD1 promoter hypermethylation increases the risk of hypertension

open access: yesClinical and Experimental Hypertension, 2019
Objectives: Methylenetetrahydrofolate dehydrogenase 1 (MTHFD1) plays an essential role in folate-mediated one-carbon metabolism which determines both homocysteine remethylation and de novo thymidylate biosynthesis.
Miao Xu   +5 more
doaj   +1 more source

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