Results 141 to 150 of about 4,473,133 (307)

Real‐World Safety of Concomitant Colchicine and Statin Therapy

Arthritis Care &Research, EarlyView.
Objective This study aimed to evaluate the risk of clinically meaningful muscle‐ and liver‐related outcomes associated with concomitant colchicine–statin therapy in a real‐world setting, and to determine whether concomitant therapy increases the incidence of toxicity compared with either agent alone.
Roni Meidan, Ranel Loutati, Dan Caspi, Ori Elkayam, Ran Abuhasira, Tali Eviatar   +5 more
wiley   +1 more source

Unsupervised Machine Learning Identifies Shared Biomechanical and Clinical Variation in Individuals with Knee Osteoarthritis and High BMI: A Secondary Analysis of the IDEA Trial

Arthritis Care &Research, Accepted Article.
Objective High body mass index (BMI≥27 kg/m2) and aberrant gait biomechanics are primary risk factors for knee osteoarthritis (KOA), yet the specific loading patterns linked to clinical disease features remain unclear. Unsupervised machine learning (ML) was used to identify vertical ground reaction force (vGRF) waveform modes of variation and ...
Ashley N. Buck, J. Elyse Borgert, Hyeon Lee, Liubov Arbeeva, Yvonne M. Golightly, Richard F. Loeser, Leigh F. Callahan, Stephen P. Messier, Brian Pietrosimone, Amanda E. Nelson, James S. Marron   +10 more
wiley   +1 more source

Untreated newly diagnosed essential hypertension is associated with nonalcoholic fatty liver disease in a population of a hypertensive center

, 2016
Spyros Michopoulos,1 Vasiliki I Chouzouri,1 Efstathios D Manios,1 Eirini Grapsa,2 Zoi Antoniou,1 Christos A Papadimitriou,3 Nikolaos Zakopoulos,1 Athanasios-Meletios Dimopoulos1 1Department of Clinical Therapeutics, Medical School of Athens, Alexandra ...
Dimopoulos AM, Chouzouri VI, Grapsa E, Michopoulos S, Antoniou Z, Papadimitriou CA, Zakopoulos N, Manios ED   +7 more
core  

The association of gout flare resolution with physical activity and sleep: a prospective remote‐monitoring study

Arthritis Care &Research, Accepted Article.
Objectives This study aimed to determine whether gout flare resolution is associated with physical activity and sleep. These findings were intended to inform the future development of a definition for flare resolution. Methods Data from 81 participants with gout who experienced >1 flare during a 6‐month prospective observational study were included ...
Sarah Stewart, Boston Girven, Mia Clarke, Irene Zeng, Angelo Gaffo, Lisa K Stamp, N Lawrence Edwards, David Rice, Tania Ka'ai, Karl Rudolph, Julie Collis, Nicola Kayes, Nicola Dalbeth   +12 more
wiley   +1 more source

Oxygen support of physical stress in perindopril-treated hypertensive patients

Кардиоваскулярная терапия и профилактика, 2005
Aim. To study and assess, with spiroergometry method, main parameters of physical stress (PS) oxygen (O2) support in arterial hypertension (AH) patients receiving combined and monotherapy with an ACE inhibitor perindopril. Material and methods. The study
V. I. Makolkin, Sh. Z. Zambakhidze, D. A. Napalkov, T. N. Apanasenko   +3 more
doaj  

Hydrogel‐Based Airway‐on‐Tube With Perfusable Endothelial Lumen and Outward Epithelialization

Advanced Materials, EarlyView.
A hydrogel‐based airway‐on‐tube platform featuring a perfusable endothelial lumen and outward epithelialization is presented. The system supports primary human bronchial epithelial and lung microvascular endothelial coculture under air‐liquid interface conditions.
Ali Doryab, Jack F. Murphy, Michael Bartolf‐Kopp, Jenny C‐C Hsin, Alice Chernaik, Frank McCaughan, Yan Yan Shery Huang, Tomasz Jungst, Jürgen Groll   +8 more
wiley   +1 more source

INSULIN RESISTANCE AND BETA-CELL HYPERSECRETION IN ESSENTIAL-HYPERTENSION

, 1990
To determine whether a decreased sensitivity to insulin is involved in the pathogenesis of essential hypertension, fasting blood glucose, serum insulin, serum C peptide, the glucose:insulin ratio and the insulin:C-peptide ratio were measured in 14 lean ...
Tedde R, Melis A, Marigliano A, Orecchioni C., Pala A, SECHI, Leonardo Alberto   +5 more
core   +1 more source

MicroRNA-155 at the crossroads of inflammation and vascular dysfunction in essential hypertension. [PDF]

Mol Biol Rep
Salamt N, Che Roos NA, Mohamed Shakrin NNS, Ugusman A.   +3 more
europepmc   +1 more source

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source

Pharmacogenomics-guided therapy for essential hypertension: a multi-center randomized controlled open-label trial. [PDF]

Front Cardiovasc Med
Wu S, Liu W, Chen L, Xu Y, Jin J, Chen F, Li J, Hu W, Wu J, Cai Y, Huang Z, Chai X, Shi X, Luo Y, Zeng G, Zeng H, Chen Z, Guo F, Wang L, Wu M, Qu Z, Wang Y, Peng D.   +22 more
europepmc   +1 more source