Genetic pathogenesis of essential arterial hypertension (the review) [PDF]
, 2011 It is proved that genetic factors may be considered as fundamental in the development of essential arterial hypertension (AH). Important role in this process belongs to the genes whose products are involved in regulating blood pressure - adrenergic ...
Borodulin V.B. +4 more
core +1 more source
Rewiring Neuroimmunity: Nanoplatform Innovations for CNS Disease Therapy
Advanced Therapeutics, EarlyView.This review explores emerging nanoplatform strategies designed to modulate neuroimmune responses for treating central nervous system (CNS) disorders. It examines structural and microenvironmental barriers, advances in multifunctional and targeted nanotechnologies, and highlights clinical progress and translational challenges, offering insights into the
Muhammad Usman Akbar +7 more
wiley +1 more source
Cytokine mRNA Delivery and Local Immunomodulation in the Placenta Using Lipid Nanoparticles
Advanced Therapeutics, EarlyView.This article evaluates lipid nanoparticles to deliver immunomodulatory mRNA to placental cells and mouse placentas to study and treat the immune underpinnings of placenta‐related diseases. Lipid nanoparticles induce cytokine secretion and macrophage polarization toward an anti‐inflammatory state.
Samuel I. Hofbauer +9 more
wiley +1 more source
THE EFFECT OF PREGNANCY ON RENAL FUNCTION IN WOMEN WITH PRE-EXISTING ESSENTIAL HYPERTENSION AND WITH CHRONIC DIFFUSE GLOMERULONEPHRITIS 1 [PDF]
, 1944 Irwin Wellen +3 more
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Relationship of daily arterial blood pressure monitoring readings and arterial stiffness profile in male patients with chronic obstructive pulmonary disease combined with arterial hypertension [PDF]
, 2013 The aim of the study was to determine correlation between arterial blood pressure daily rhythm and daily profile of arterial stiffness in male patients with chronic obstructive pulmonary disease (COPD) and arterial hypertension.
Borodkin A.M. +3 more
core
Advanced Science, EarlyView.Extracellular matrix remodeling is crucial in cancer progression. Using a peptide to probe the tension of ECM fibers, it was found that Fibronectin fibers gradually lose tension as human breast carcinoma progresses, while their tension is maintained in ductal carcinoma in situ (DCIS), the non‐invasive precursor of breast cancer. This loss of tension is
Arnaud Miéville +6 more
wiley +1 more source
Cerebral Oxygen Consumption in Essential Hypertension Constancy with Age, Severity of the Disease, Sex, and Variations of Blood Constituents, As observed In 101 Patients1 [PDF]
, 1954 Joseph H. Hafkenschiel +2 more
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JUS SELEDRI (APIUM GRAVEOLENS) MENURUNKAN TEKANAN DARAH PADA PASIEN DENGAN HIPERTENSI ESSENSIAL [PDF]
, 2015 Hypertension is a common public health problem. Uncontrolled hypertension can lead to degenerative diseases, such as congestive heart failure, kidney failure, and vascular disease. Hypertension is called “silent killer”.
Abdul Majid, +2 more
core
Bilirubin Targeting WNK1 to Alleviate NLRP3‐Mediated Neuroinflammation
Advanced Science, EarlyView.At physiological concentrations, bilirubin binds to the kinase domain of WNK1, thereby augmenting its activity and facilitating the phosphorylation of downstream SPAK/OSR1. This phosphorylation inhibits KCC2 activity, leading to elevate intracellular chloride levels in neurons.
Linfei Mao +14 more
wiley +1 more source
Certain Modifiable Risk Factors in Essential Hypertension: A Case- Control Study
National Journal of Community Medicine, 2011 Essential hypertension accounts for 90% of all cases of hypertension. Though it is a one of major risk factors for cardiovascular diseases, it is a condition with its own risk factors.
Sunil M. Sagare +2 more
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