Results 231 to 240 of about 899,582 (283)

Differential methylation in blood pressure control genes is associated to essential hypertension in African Brazilian populations. [PDF]

Epigenetics
Avila Martins CC, Maschietto M, Kimura L, Alvizi L, Nunes K, Magalhães Borges V, Victorino Krepischi AC, Mingroni-Netto RC.   +7 more
europepmc   +1 more source

Tobacco Smoke Exposure From Prenatal To Adolescent Periods Drives IBD Pathogenesis: Dynamic DNA Methylation Signatures Across Lifespan Stages

Advanced Science, EarlyView.
This study illustrates that maternal smoking during pregnancy (MSDP) is an independent risk factor for IBD in offspring, and DNA methylation serves as a key mechanistic pathway connecting early‐life smoking exposure with IBD risk in offspring. That highlights the urgent need for preventive interventions targeting prospective parents and minors to ...
Han Zhang, Jianhui Zhao, Jie Chen, Xinyi Ma, Siyun Zhou, Alexandra Noble, Rahul Kalla, Judith Wellens, Kun Liu, Evropi Theodoratou, Jack Satsangi, Xue Li   +11 more
wiley   +1 more source

A Clinical Study on the Efficacy of Acupuncture Treatment in Essential Hypertension: Protocol for Randomized Controlled Trial.

JMIR Res Protoc
Hao X, Zhang L, Gong Y, Wang J, Qin W, Zhang X, Guo Q, Xu M, Lv T, Guo Y, Liu Y, Liu J, Yue B, Liu Q.   +13 more
europepmc   +1 more source

Prevalence and clinical correlates of microalbuminuria among patients of essential hypertension in tertiary care center of Nepal: A cross-sectional study. [PDF]

Medicine (Baltimore)
Lamsal L, Joshi R, Bhattarai M, Parajuli B, Timilsina S, Kunwor B, Chhetri S, Bhandari S, Chaurel A, Bhattarai HB.   +9 more
europepmc   +1 more source

Islet Amyloid Polypeptide Modelled to Simulate Diabetes Co‐Oligomerized with β‐Amyloid 1‐42 Reproducing the Pathological Cascade of Alzheimer's Disease in Human Cerebral Organoids

Advanced Science, EarlyView.
Human islet amyloid polypeptide (hIAPP) was used to mimic T2DM, and Aβ42‐hIAPP co‐oligomers were delivered into the human mature cerebral organoids (COs), which reproduce typical AD pathology and significant neuronal death more closely resembling that of AD patients.
Jin Yan, Zhimeng Tang, Yanyu Luo, Bin Liu, Xinxin Huang, Jun Wei, Feng Yue   +6 more
wiley   +1 more source

Associations of Metabolites Related Salt Sensitivity of Blood Pressure and Essential Hypertension in Chinese Population: The EpiSS Study. [PDF]

Nutrients
Yang X, Zhang F, Zhang B, Qi H, Xie Y, Peng W, Li B, Wen F, Li P, Sun Y, Qu A, Zhang L.   +11 more
europepmc   +1 more source

Prevalence of Microalbuminuria in Essential Hypertension and its Association with Coronary Artery Disease: A Cross-sectional Study

Jagannath S Dhadwad, Kunal Modi
openalex   +1 more source

Caspase‐3/GSDME‐Mediated Trophoblast Pyroptosis and Reciprocal Macrophage Polarization Contribute to Inflammation in Early‐Onset Preeclampsia

Advanced Science, EarlyView.
In trophoblast cells, T/S (TNFα + SM164) activated caspase‐3, which cleaved GSDME to switch apoptosis to pyroptosis, causing cell swelling, membrane rupture, and release of LDH, HMGB1, IL‐1β and IL‐18. These cytokines induced pro‐inflammatory macrophage polarization, which in turn reinforced pyroptotic signaling in trophoblasts, amplifying systemic ...
Baoying Huang, Weinan Deng, Shilei Bi, Yifan Wang, Zhaowei Tu, Lijun Huang, Lili Du, Lizi Zhang, Zhoushan Feng, Wei Sun, Tengfei Liu, Julia Kzhyshkowska, Haibin Wang, Jingsi Chen, Dunjin Chen, Shuang Zhang   +15 more
wiley   +1 more source

Obesity, Visceral Adipose Tissue, and Essential Hypertension: Evidence From a Mendelian Randomization Study and Mediation Analysis. [PDF]

J Clin Hypertens (Greenwich)
Cheng C, Li Z, Su Y, Sun JY, Xu CH, Kong XQ, Sun W.   +6 more
europepmc   +1 more source