Results 171 to 180 of about 1,901,618 (330)

IκB kinase-induced interaction of TPL-2 kinase with 14-3-3 is essential for Toll-like receptor activation of ERK-1 and -2 MAP kinases

, 2014
Abduelhakem Ben-Addi, Agnes Mambole-Dema, Christine Brender, Stephen R. Martin, Julia Janzen, Susanne K. Kjær, Stephen J. Smerdon, Steven C. Ley   +7 more
openalex   +1 more source

Expression and DNA methylation of 20S proteasome subunits as prognostic and resistance markers in cancer

Molecular Oncology, EarlyView.
Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla, Simone Venz, Ruslan Al‐Ali, Martin Wendlandt, Mandy Radefeldt, Elke Krüger   +5 more
wiley   +1 more source

3D-LAKES: Three-Dimensional Global Lake and Reservoir Bathymetry from ICESat-2 Altimetry and Landsat Imagery. [PDF]

Sci Data
Huang CH, Zhang S, Shah D, Yadav A, Li Y, Zhao G, Gao H.   +6 more
europepmc   +1 more source

Essential Role of p38α MAP Kinase in Placental but Not Embryonic Cardiovascular Development [PDF]

, 2000
Ralf H. Adams, Almudena Porrás, Gema Alonso, Margaret A. Jones, Kristina Vintersten, Simona Panelli, Amparo Valladares, Lídia Pérez, Rüdiger Klein, Ángel R. Nebreda   +9 more
openalex   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Coincidence type alternatives for Φ --essential maps

, 2016
Donal O’Regan
openalex   +2 more sources

MAP kinase pathway signalling is essential for extracellular matrix determined mammary epithelial cell survival [PDF]

, 2000
Darren Finlay, Vincent Healy, Fiona Furlong, F C O'Connell, Niamh Keon, F. Martin   +5 more
openalex   +1 more source

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

Molecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh, Nikola Tom, Anna Schrøder Lassen, Helene Brasch Lind Petersen, Ulrik Kristoffer Stoltze, Karin Wadt, Kjeld Schmiegelow, Matteo Tiberti, Elena Papaleo   +8 more
wiley   +1 more source

Correction: Inclusion of a microencapsulated pepper, cashew nut, and copaiba essential oils blend in broiler feed: evaluation of performance and nutrient metabolizability. [PDF]

Trop Anim Health Prod
Corrêa JHM, Laurentiz AC, Rondis CCSF, Filardi RDS, Oliveira ES, Laurentiz RDS.   +5 more
europepmc   +1 more source

MicroRNA 196a contributes to the aggressiveness of esophageal adenocarcinoma through the MYC/TERT/NFκB axis

Molecular Oncology, EarlyView.
mir‐196a promotes Esophagus Adenocarcinoma aggressiveness. On one hand, mir‐196a targets the valosin‐containing protein (VCP) mRNA, causing the accumulation of c‐MYC protein that leads to high amounts of TERT. On the other hand, mir‐196a targets the inhibitor of NFκB (NFKBIA).
Jesús García‐Castillo, Carlos M. Martínez‐Cáceres, Manuel Bernabé‐García, Vicente Munitiz, David Ruiz de Angulo, Pascual Parrilla, Ángeles Ortiz, Luisa F. Martínez de Haro, María L. Cayuela   +8 more
wiley   +1 more source