Results 201 to 210 of about 195,292 (253)

Correction: A randomised survey of the quality of antibiotics and other essential medicines in Indonesia, with volume-adjusted estimates of the prevalence of substandard medicines. [PDF]

PLOS Glob Public Health
Pisani E, Rahmawati A, Mulatsari E, Rahmi M, Nathanial W, Anggriani Y, STARmeds Study Group.   +6 more
europepmc   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Longitudinal Trends in Medicine Supply, Price and Utilisation in Primary Care Facilities in Rural Southwestern China Under National Essential Medicines Policy (2012-2017): Disparities Across Facilities and Medicines. [PDF]

Int J Health Policy Manag
Huo Z, Xiong X, Bai G, Quan J, Lee AT, Lam LC, Luo L.   +6 more
europepmc   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Availability, price and affordability of essential medicines for managing cardiovascular disease in Addis Ababa, Ethiopia. [PDF]

Sci Rep
Masresha R, Habte F, Senbeta MF, Baye AM, Kassaw C, Beyene MG.   +5 more
europepmc   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Cardiovascular disease essential medicines listing by countries: changes over time and association with health outcomes. [PDF]

BMC Cardiovasc Disord
Heredia C, Ul Haq MZ, Buadu A, Rizvi A, Workentin A, Persaud N.   +5 more
europepmc   +1 more source

Setting standards for essential children's medicines

Bulletin of the World Health Organization, 2007
Suzanne R Hill, Andy Gray, Martin Weber
doaj  

Essential medicines in Central America: Analysis of national lists, macroeconomic factors, and alignment with health priorities. [PDF]

J Med Access
Martínez-Vargas E, Arguedas-Chacón S, González-Rodríguez V, Mora-Jiménez J, Cruz-Mora K, Zavaleta-Monestel E.   +5 more
europepmc   +1 more source

Availability of essential medicines for maternal health in public health facilities of the Mwanza region, northwestern Tanzania. [PDF]

J Med Access
Mayunga C, Msaki E, Katabalo D, Mwita S.
europepmc   +1 more source