Results 101 to 110 of about 227,175 (284)

Latest clinical recommendations on valproate use for migraine prophylaxis in women of childbearing age. Overview from European Medicines Agency and European Headache Federation [PDF]

, 2018
Migraine is a common and burdensome neurological condition which affects mainly female patients during their childbearing years. Valproate has been widely used for the prophylaxis of migraine attacks and is also included in the main European Guidelines ...
Dogne, Jean-Michel, Garcia Burgos, Juan, Girard, Thomas, Martelletti, Paolo, Straus, Sabine, Vatzaki, Efstratia   +5 more
core   +2 more sources

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Pediatric formulations in national essential medicines lists: a cross-sectional study

Frontiers in Pediatrics
BackgroundChildren need specialized medicine formulations for proper dosing, safety, and adherence. The World Health Organization developed a pediatric essential medicines list prioritising pediatric formulations.
Camila Heredia, Moizza Zia Ul Haq, Bernadette Cappello, Farihah Malik, Martina Penazzato, Lorenzo Moja, Navindra Persaud, Navindra Persaud   +7 more
doaj   +1 more source

A survey of availability, price and affordability of essential medicines from 2011 to 2016 in Chinese secondary and tertiary hospitals

International Journal for Equity in Health, 2018
Background Essential medicines are those drugs that satisfy the priority health care needs of the population and help with functioning healthcare systems.
Xiaodong Guan, Huajie Hu, Chunxia Man, Luwen Shi   +3 more
doaj   +1 more source

Review of medicine registration system in Tanzania [PDF]

, 2019
Philosophiae Doctor - PhDRegistration of medicines is an essential function of the national medicine regulatory system of any country. Since the start of the medicine registration system in Tanzania in early 2000s, no systematic review has been carried
KISOMA, SUNDAY
core  

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Compulsory Licensing of Patented Pharmaceutical Inventions: Evaluating the Options [PDF]

, 2009
In this Comment, the author traces the relevant legislative history pertaining to compulsory licensing of patented pharmaceuticals from the TRIPS Agreement of 1994 to the 2003 waiver to, and later proposed amendment of, article 31, which enables poor ...
Arezzo, Coco, Danzon, Danzon, Debrulle, Drahos, Drexl, Fox, Hovenkamp, Hovenkamp, Jerome H. Reichman, Love, Lybecker, Maskus, Mercurio, Mercurio, Moran, Outterson, Reichman, Reichman, Reichman, Watal, Yu   +22 more
core   +2 more sources

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Making the List: The Role of Essential Medicines Lists In Reproductive Health

International Perspectives on Sexual and Reproductive Health, 2010
After immunization for common childhood illnesses, appropriate use of essential medicines is one of the most cost-effective components of modern health care. (1) Many interventions for communicable and noncommunicable diseases and conditions that threaten maternal and child health rely on the use of these high-quality medicines.
Jane, Hutchings, Keith, Neroutsos, Kathleen, Donnelly   +2 more
openaire   +2 more sources

Essential medicines: An Indian perspective

Indian Journal of Community Medicine, 2015
The concept of defining essential medicines and establishing a list of them was aimed to improve the availability of affordable medicines for the world′s poor. Access to essential medicines is a major determinant of health outcomes.
Rituparna Maiti, Vikas Bhatia, Biswa Mohan Padhy, Debasish Hota   +3 more
doaj   +1 more source