Results 121 to 130 of about 4,637,538 (347)
Molecular Oncology, EarlyView.This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu +12 more
wiley +1 more source
Norma policéntrica del español frente a la traducción jurídica polaco‑española
Między Oryginałem a Przekładem, 2016 Polycentric Spanish Norm Towards the Polish‑Spanish Legal Translation The Spanish, being the official language of Spain and many other countries, is characterized by an important dialectal diversity that is reflected in the differences at all ...
Piotr Sorbet
doaj +1 more source
Molecular Oncology, EarlyView.This nationwide study evaluated KRAS and NRAS mutations in 10 754 Turkish patients with metastatic colorectal cancer. The results revealed a mutation frequency of 51.1%, with 46.6% having KRAS mutations, 4.5% having NRAS mutations, and 48.5% being wild‐type for both.
Gozde Kavgaci +6 more
wiley +1 more source
An A Posteriori Error Indicator for Discontinuous Galerkin Approximations of Fourth Order Elliptic Problems [PDF]
We introduce a residual-based a posteriori error indicator for discontinuous Galerkin discretizations of the biharmonic equation with essential boundary conditions.
Georgoulis, Emmanuil H. +2 more
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Molecular Oncology, EarlyView.This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh +8 more
wiley +1 more source
Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer
Molecular Oncology, EarlyView.Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte +10 more
wiley +1 more source
Residential Mobility Decreases Neural Responses to Social Norm Violation
Frontiers in Psychology, 2019 Social norms are essential, but they vary across cultures and societies. With the internationalization of human society, population mobility has greatly increased, especially in developing countries, which can have an impact on people’s psychological ...
Siyang Luo +6 more
doaj +1 more source
On the Essential Norm of the Double Layer Potential on Polyhedral Domains and the Stability of the Collocation Method [PDF]
, 2001 Olaf Hansen
openalex +1 more source
Molecular Oncology, EarlyView.The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song +11 more
wiley +1 more source
, 2017 This paper continues the research started in \cite{LW16}. In the framework of the convolution structure density model on $\bR^d$, we address the problem of adaptive minimax estimation with $\bL_p$--loss over the scale of anisotropic Nikol'skii classes ...
Lepski, Oleg, Willer, Thomas
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