Results 111 to 120 of about 3,279,270 (293)

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Unemployment as a Social Norm in Germany [PDF]

open access: yes
This paper investigates the relationship between the subjective well-being of both the employed and unemployed and regional unemployment rates. While employed men suffer from regional unemployment, unemployed men are significantly less negatively ...
Andrew E. Clark   +2 more
core   +2 more sources

Residential Mobility Decreases Neural Responses to Social Norm Violation

open access: yesFrontiers in Psychology, 2019
Social norms are essential, but they vary across cultures and societies. With the internationalization of human society, population mobility has greatly increased, especially in developing countries, which can have an impact on people’s psychological ...
Siyang Luo   +6 more
doaj   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

An analysis of norm emergence in Axelrod's model [PDF]

open access: yes, 2010
Norms are a valuable mechanism for establishing coherent cooperative behaviour in decentralised systems in which no central authority exists. One of the most influential formulations of norm emergence was proposed by Axelrod, who defined a model of norms
Mahmoud, Samhar   +3 more
core  

Maximum norm a posteriori error estimation for parabolic problems using elliptic reconstructions [PDF]

open access: yes, 2013
A semilinear second-order parabolic equation is considered in a regular and a singularly perturbed regime. For this equation, we give computable a posteriori error estimates in the maximum norm.
NATALIA KOPTEVA (12353197)   +5 more
core   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Growth Spaces on Circular Domains Taking Values in a Banach Lattice, Embeddings and Composition Operators

open access: yesMathematics
We introduce the space of holomorphic growth spaces with values in a Banach lattice. We provide norm and essential norm estimates of the embedding operator, and we completely characterize the bounded and compact embeddings of the growth spaces using ...
Nihat Gökhan Göğüş
doaj   +1 more source

THE STUDY OF BIOLOGICAL VALUE OF QUINOA SEEDS (CHENOPODIUM QUINOA WILLD.) TO CREATE SPECIALIZED FOOD PRODUCTS [PDF]

open access: yesТехника и технология пищевых производств, 2016
Nowadays, an important part of the world food problem is a shortage of protein in the diet. This is a complicated problem, the significance of which is related to the special role of protein in a human life. The negative dynamics of protein value changes
Shchekoldina T.V.   +2 more
doaj  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

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