Results 91 to 100 of about 3,430,711 (291)

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

On the Essential Norm of Multiplications Operators Acting on Cesàro Sequence Spaces

open access: yesJournal of Function Spaces, 2019
In this article, we establish an important property about the growth of sequences in the dual space of Cesàro sequence spaces. As a consequence of this fact, we calculate the measure of noncompactness or the essential norm of the multiplication operator ...
Julio C. Ramos-Fernández   +2 more
doaj   +1 more source

Norm Durant

open access: yes, 2007
"S 36758 Cpl Norm Durant N.T. Force Sigs Coomalie Creek [M obscured Sept 19]43".S 36758 Corporal Norm Durant.
Durant, Norm
core  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

The essential norm of a composition operator mapping into Qk type spaces

open access: yesJournal of Function Spaces and Applications, 2008
An asymptotic formula for the essential norm of the composition operator Cφ(f):=f∘φ, induced by an analytic self-map φ of the unit disc, mapping from the α-Bloch space ℬα or the Dirichlet type space Dαp into Qk(p,q) is established in terms of an integral
Marko Kotilainen, Jouni Rättyä
doaj   +1 more source

Norm Smith

open access: yes, 2007
"Bombardier Norm Smith 1/54th A.A. S/lights. Known as "Boonga." P/C. Vestey's, Picnic Cove S/light. Sites."Bombardier Norm Smith 1/54th Anti Aircraft Searchlights.
Smith, Norm
core  

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Interpolation of the essential spectrum and the essential norm [PDF]

open access: yesBanach Center Publications, 2005
A. G. Aksoy, H.-O. Tylli
openaire   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

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