Results 211 to 220 of about 78,423 (261)

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

The Rlign algorithm for enhanced electrocardiogram analysis through heart rate-corrected ECG alignment for explainable classification and clustering. [PDF]

Eur Heart J Digit Health
Plagwitz L, Bickmann L, Fujarski M, Brenner A, Gobalakrishnan W, Eckardt L, Büscher A, Varghese J.   +7 more
europepmc   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

Efficient High-Resolution Sparse Channel Estimation Based on Temporal Correlation in MIMO-OFDM Systems. [PDF]

Sensors (Basel)
Xie H, Wang Y, Andrieux G, Men S.
europepmc   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Threats and deprivations as predictors of IPV perpetration: a cross-sectional analysis of a nationally representative sample of Bangladeshi young adults. [PDF]

BMJ Open
Islam A, Haque M, Chowdhury MS.
europepmc   +1 more source

Heterotropic regulation and negative homotropic cooperativity

FEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea, Francesco Angelucci, Federica Arnesano, Gianmarco Pascarella, Patrizio Di Micco, Andrea Bellelli   +5 more
wiley   +1 more source

What drives people to play pickleball? A mixed-methods study using SEM and fsQCA. [PDF]

Front Psychol
Huang W, Xiao D, Cheng B.
europepmc   +1 more source

When resources run short: the inhibitory effect of economic scarcity on third-party punishment. [PDF]

Front Psychol
Liang H, Li J.
europepmc   +1 more source

Enhancing the Short Physical Performance Battery: Proposing Norm Values for the 4-Meter Walking Test for Multimorbid Older Adults. [PDF]

Clin Interv Aging
Labott BK, Belkin V, Wollesen B, Voelcker-Rehage C.   +3 more
europepmc   +1 more source