Results 61 to 70 of about 19,765 (204)

O‐GlcNAcylated TAP1 Impairs Antigen Presentation and Promotes Immune Evasion in Bladder Cancer

Advanced Science, EarlyView.
This article unveils a critical mechanism of immune evasion in bladder cancer, which the O‐GlcNAc modification of TAP1 disrupts antigen presentation. This modification triggers HLA‐A degradation, shielding tumor cells from CD8+ T cell attack. The findings highlight targeting this pathway as a promising therapeutic avenue to sensitize tumors to ...
Jinpeng Wu, Xueting Ren, Zhen Zhai, Lu Wang, Liang Liang, Zengqi Tan, Jiazhen Zhao, Yuxuan Han, Yuhan Li, Feng Guan, Xiang Li   +10 more
wiley   +1 more source

Corals and Reef‐Dwelling Fish Regulate Carbon Storage and Cycling Processes in Coral Reef Ecosystems

Advanced Science, EarlyView.
Coral reefs are biodiversity hotspots, yet their role in carbon storage and cycling remains poorly understood. Using field surveys and modeling in the South China Sea, we reveal the overlooked potential of carbon storage in reef ecosystems and how reef fish, corals, and surface sediment jointly shape reef carbon reservoirs.
Yiting Chen, Wenliang Zhou, Lan Qiu, Han Lai, Mingpan Huang, Qian Li, Wen Yu, Pei‐Yuan Qian, Fuwen Wei   +8 more
wiley   +1 more source

Ultrasound‐Activated Bifunctional Piezoelectric Hydrogel Dressings Promote Infected Wound Healing via Regulating Angiogenesis and Lymphangiogenesis

Advanced Science, EarlyView.
This study developed a double‐network hydrogel with piezoelectric properties, exhibiting excellent antibacterial activity and promoting fibroblast migration, angiogenesis, and lymphangiogenesis through piezoelectric stimulation, thereby accelerating the healing of infected chronic wounds.
Xiang Li, Zhen Ding, Zhihua Liu, Hao Chen, Jianyang Shan, Yanxuan Shao, Yaling Yu, Gen Wen   +7 more
wiley   +1 more source

Multidisciplinary Scientific Cruises for Environmental Characterization in the Santos Basin – Methods and Sampling Design

Ocean and Coastal Research
The Santos Basin (SB) is the main petroliferous basin in the Brazilian continental margin and one of the most studied marine areas in Brazil. However, historical data suggest that new efforts should be carried out to acquire quantitative biological data,
Daniel L. Moreira, Adriana G. Dalto, Alberto G. Figueiredo Jr Figueiredo Jr, Aline M. Valerio, Amalia M. S. Detoni, Ana C. T. Bonecker, Camila N. Signori, Cláudia Namiki, Dalton K. Sasaki, Daniel V. Pupo, Danilo A. Silva, Deborah S. Kutner, Diana C. Duque-Castaño, Eduardo H. Marcon, Fabiana D. C. Gallotta, Fabiana S. Paula, Fabiane Gallucci, Gabriela C. F. Roque, Giulia S. Campos, Gustavo Fonseca, Gustavo Mattos, Helena P. Lavrado, Ilson C. A. da Silveira, Jessica O. Costa, João R. dos Santos Filho, Juliane C. Carneiro, Julio C.F. Moreira, Laura Rozo, Leandro F.M. Araujo, Letícia Lazzari, Letícia O. da Silva, Luan S. Michelazzo, Luciano F. Fernandes, Marcelo Dottori, Marcus A. G. de Araújo Jr., Mateus G. Chuqui, Milena Ceccopieri, Milton Borges-Silva, Milton Kampel, Natascha M. Bergo, Paulo V. M. Silva, Pedro M. Tura, Rafael B. de Moura, Renato G. Romano, Renato P. Martins, Renato S. Carreira, Rodrigo G.A. Toledo, Sérgio L.C. Bonecker, Sibelle T. Disaró, Silvana V. Rodrigues, Thais N. Corbisier, Thaisa M. Vicente, Vitor G. de Paiva, Vivian H. Pellizari, Wellington C. Belo, Frederico P. Brandini, Silvia H.M Sousa   +56 more
doaj   +2 more sources

Two Routes to Land: Genomic Underpinnings of Parallel Aerial Egg Deposition in Aquatic Old‐World Pila and New‐World Pomacea (Ampullariidae)

Advanced Science, EarlyView.
Comparative genomics of Gondwana‐diverged Pila and Pomacea reveals parallel evolution of aerial oviposition. Convergent chromosomal rearrangements reshape regulatory landscapes within topologically associating domains. Lineage‐specific gene family expansions and viral‐derived perivitelline proteins (PV1) underpin desiccation resistance.
Yufei Zhou, Huawei Mu, Xueying Nie, Yue Gao, Hui Wang, Ling Fang, Tiangang Luan, Monthon Ganmanee, Jian‐Wen Qiu, Jin Sun, Jack Chi‐Ho Ip   +10 more
wiley   +1 more source

Heterointerface Engineering of Bismuth Nanosheets/Nitrogen‐Doped Carbon Nanoleaves Enables High‑Performance Electrochemical Dechlorination

Advanced Science, EarlyView.
Bismuth nanosheets integrated with nitrogen‐doped carbon nanoleaves are constructed via a 2D‐on‐2D heterointerface engineering strategy. The resulting BiNS/NCL electrode delivers high chloride adsorption capacity, fast kinetics, and stable cyclability. A built‐in electric field at the heterointerface promotes chloride electrosorption and stabilizes the
Bohan Liu, Feifei Pang, Xingtao Xu, Duo Yang, Xi Yu, Sikan Yang, Jiarui Hao, Nithima Khaorapapong, Zhichang Xiao, Xiaoxian Zhao, Yusuke Yamauchi, Shuaihua Zhang   +11 more
wiley   +1 more source

A Universal Approach to Enhancing Silicon Hot‐Carrier Photodetectors for CMOS‐Compatible SWIR Imaging

Advanced Science, EarlyView.
Silicon hot‐carrier photodetectors offer a CMOS‐compatible pathway for SWIR detection but suffer from intrinsically low quantum efficiency. Here, we introduce a quasi‐generalized antireflection coating (QARC) that universally enhances optical absorption and quantum efficiency, enabling the first CMOS‐compatible SWIR imaging with silicon hot‐carrier ...
Eui‐Hyoun Ryu, Hyun Woo Ko, Sunghyun Hwang, Nayeon Kim, Ji‐Hwan Son, Sunghyun Han, Paul Hongsuck Seo, Jisoo Hong, Sang‐Jun Kim, Seon Kyu Yoon, Min‐Chul Park, In‐Ho Lee   +11 more
wiley   +1 more source

Natural Resistance to Ovarian Hyperstimulation Syndrome in Estrildid Finches Reveals Macrophage GPR183 as a Potential Therapeutic Target

Advanced Science, EarlyView.
Ovarian macrophage depletion reverses OHSS resistance in estrildid finches and exacerbates OHSS symptoms in rats. Activating macrophage GPR183 alleviates OHSS by reducing pro‐inflammatory factors, increasing immunomodulatory molecules, remodeling CD44/SDC4‐mediated communication, and restoring immune homeostasis.
Xiaofei Yan, Yongjie Huang, Jiabao Yang, Su Ma, Songsong Liu, Xuan Huang, Juergen Brosius, Huaping Zheng, Bing Yao, Li Chen, Shanshan Lai, Cheng Deng   +11 more
wiley   +1 more source

Heterojunction‐Engineered Mass Spectrometry Platform for Deciphering Serum Metabolic Fingerprints in Diagnosis of Respiratory Diseases

Advanced Science, EarlyView.
Hollow Co3O4/TiO2 heterojunctions are engineered for high‐throughput laser desorption/ionization mass spectrometry. The built‐in electric field drives efficient charge separation and photothermal conversion, while the hierarchical mesoporous network enables robust salt and protein tolerance.
Junyu Chen, Chaoqi Wang, Xi Yu, Yuming Jiang, Yijiao Qu, Huihui Fu, Yuyin Bu, Xiaoyong Zhang, Zongxiu Nie   +8 more
wiley   +1 more source

Drop‐Shaped Optical Microfiber Enabled Biomechanical Sensor

Advanced Science, EarlyView.
A novel microforce sensor based on a drop‐shaped optical microfiber is presented herein, designed to characterize the biomechanical properties of single cells and microscale living organisms, achieving a force resolution of 24 nN. Leveraging its high sensitivity, facile miniaturization, excellent flexibility, and robust mechanical stability, this ...
Yan Xu, Xitao Tu, Haochen Jiang, Jun Mo, Xinyue Zhang, Xiaomin Yue, Limin Tong, Lei Zhang   +7 more
wiley   +1 more source