Results 41 to 50 of about 6,272,398 (259)
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Журнал органічної та фармацевтичної хімії, 2021 Aim. To study the qualitative composition and the quantitative content of the essential oil components from Laurus nobilis L. unripe fruits. Results and discussion. In the essential oil from Laurus nobilis L.
Irina Yu. Posohova +3 more
doaj +1 more source
Variability of essential oil composition of wormwood (Artemisia absinthium L.) affected byplant organ [PDF]
, 2016 The essential oil composition of leaves and roots of twenty individuals of wormwood (Artemisia absinthium L.) belonging to different chemotypes has been investigated.
Castell-Zeising, Vicente +3 more
core +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
, 2007 Essential oils of aerial parts of the Satureja cuneifolia were extracted by simultaneous distilation-exraction and analyzed by gas chromatography-mass spectrometry (GC-MS).
Altun, M., Goren, A. C.
core +1 more source
Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers
FEBS Letters, EarlyView.Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui +4 more
wiley +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Chemical composition and antimicrobial activity of Marrubium deserti de Noé essential oil
Chemistry Journal of Moldova: General, Industrial and Ecological ChemistryThe main objectives of this study were to determine the chemical composition of the essential oil of Marrubium deserti de Noé (EOMD) from Bechar (Algeria), and to evaluate its physicochemical properties, antibacterial and antifungal activities. The yield
Amina Mazeri +4 more
doaj +1 more source
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source