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New England Journal of Medicine, 2018 Essential tremor (ET) is one of the most common neurologic disorders, and genetic factors are thought to contribute significantly to disease etiology. There has been a relative lack of progress in understanding the genetic etiology of ET. This could reflect a number of factors, including the presence of substantial phenotypic and genotypic ...
Lorraine N, Clark, Elan D, Louis
exaly +13 more sources
Essential tremor: clinical observations [PDF]
Arquivos de Neuro-Psiquiatria, 1993 The authors have studied 53 patients with essential tremor, focusing its clinical and epidemiological aspects. There were familial history in 37.70% of all cases, prevailing in females (56.60%) and white people (69.80%); nevertheless this difference can ...
João S. Pereira +2 more
doaj +5 more sources
JAMAThis JAMA Insights discusses the diagnostic evaluation and treatment, including pharmacological, nonpharmacological, and surgical options, of essential tremor.
Edson Cataldo
+6 more sources
Romanian Medical Journal, 2015 Essential tremor is a frequent disease, but rather often under-diagnosed, due to the fact that the patients with mild essential tremor don’t visit the neurologist, or due to some confusion in establishing the diagnosis in advanced stages of the disease.
core +2 more sources
Harmaline Tremor: Underlying Mechanisms in a Potential Animal Model of Essential Tremor [PDF]
Tremor and Other Hyperkinetic Movements, 2012 Background: Harmaline and harmine are tremorigenic β-carbolines that, on administration to experimental animals, induce an acute postural and kinetic tremor of axial and truncal musculature.
Adrian Handforth
doaj +5 more sources
Medical Clinics of North America, 2019 Essential tremor is one of the most common movement disorders. It is characterized by a bilateral action tremor of the upper limbs. It may be accompanied by tremor of the head, voice, or lower limbs. Essential tremor is often present for years or decades before presentation and it progresses insidiously.
Karoline, Flengsrud +2 more
+8 more sources
Multimodal imaging of essential tremor and dystonic tremor
NeuroImage: Clinical, 2022 Despite recent advances in tremor and dystonia classification, it remains difficult to discriminate essential tremor from dystonic tremor as they are similar in appearance and no biomarker exists.
Patrick Bédard +4 more
doaj +1 more source
Canadian Medical Association Journal, 2017 Essential tremor (ET) is the most common cause of tremor. Most studies suggest that the cerebellum is involved in the pathophysiology of ET and that it is an autosomal dominant disorder; however, the actual cause and a gene responsible for the majority of cases have not been identified.
Graeme, Schwindt, Jeremy, Rezmovitz
openaire +3 more sources
Propranolol significantly reduced DNA polymerase β expression in patients with essential tremor
Universa Medicina, 2021 Background Essential tremor (ET) is the most common movement disorder. Propranolol is a first-line medication for ET. We aimed to evaluate the effect of propranolol on the expression of poly (ADP-ribose) polymerase 1 (PARP1) and DNA polymerase beta ...
Nefise Kandemir +8 more
doaj +1 more source
Managing Essential Tremor [PDF]
Neurotherapeutics, 2020 Essential tremor is one of the most common tremor syndromes. According to the recent tremor classification, tremor as a symptom is defined as an involuntary, rhythmic, oscillatory movement of a body part and is classified along two axes: axis 1-defining syndromes based on the clinical features such as historical features, tremor characteristics ...
Franziska Hopfner, Günther Deuschl
openaire +3 more sources