Results 91 to 100 of about 1,306,145 (264)

Higher-Order Convolutional Neural Networks for Essential Climate Variables Forecasting

Remote Sensing
Earth observation imaging technologies, particularly multispectral sensors, produce extensive high-dimensional data over time, thus offering a wealth of information on global dynamics.
Michalis Giannopoulos, Grigorios Tsagkatakis, Panagiotis Tsakalides   +2 more
doaj   +1 more source

How Essential Biodiversity Variables and remote sensing can help national biodiversity monitoring

Global Ecology and Conservation, 2017
Essential Biodiversity Variables (EBVs) have been suggested to harmonize biodiversity monitoring worldwide. Their aim is to provide a small but comprehensive set of monitoring variables that would give a balanced picture of the development of ...
Petteri Vihervaara, Ari-Pekka Auvinen, Laura Mononen, Markus Törmä, Petri Ahlroth, Saku Anttila, Kristin Böttcher, Martin Forsius, Jani Heino, Janne Heliölä, Meri Koskelainen, Mikko Kuussaari, Kristian Meissner, Olli Ojala, Seppo Tuominen, Markku Viitasalo, Raimo Virkkala   +16 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Essential Ocean Variables and Essential Climate Variables Framework - OBPS workshop

Presentation delivered at Ocean Best Practices Workshop, online, on 16 October 2024. Part of the session "The WMO Rolling Review of Requirements and application areas for Essential Ocean Variables and Essential Climate Variables" organized by ObsSea4Clim project.
openaire   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Definition of Essential Geodetic Variables (EGVs)

, 2022
Essential Geodetic Variables (EGVs) are observed variables that are crucial (essential) to characterizing the geodetic properties of the Earth and that are key to sustainable geodetic observations. Examples of EGVs might be the positions of reference objects (ground stations, radio sources), Earth orientation parameters, ground- and space-based gravity
openaire   +2 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source