Results 31 to 40 of about 182,430 (285)
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
José Lins do Rego: um guia brasileiro de Israel
Arquivo Maaravi: Revista Digital de Estudos Judaicos da UFMG, 2010 Este artigo procura analisar, de forma crítica, o livro de José Lins do Rego, Roteiro de Israel, 1955. Busca-se destacar duas facetas suplementares: a de um olhar poético e a de uma preocupação ético-política lançados pelo escritor sobre a construção do
Glauber Pereira Quintão
doaj +1 more source
“Tanques contra piedras”: la imagen de Israel en España [PDF]
, 2007 Este trabajo analiza el problema de la imagen de Israel en España, cuya opinión pública muestra niveles de distanciamiento y hostilidad más pronunciados que en los demás países de Europa.
Baer, Alejandro
core
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
De actor secundário a actor principal : o Supremo Tribunal e a "revolução constitucional" em Israel [PDF]
, 2007 Analisa o surgimento do Estado de Israel e de suas instituições, apontando os problemas do judiciário israelita. Em seguida, discorre sobre a "revolução constitucional" ocorrida no país na década de 90 e conclui que a criação do Estado laico constituiu ...
Pereira, J. A. Teles
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Remote Monitoring in Myasthenia Gravis: Exploring Symptom Variability
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Myasthenia gravis (MG) is a rare, autoimmune disorder characterized by fluctuating muscle weakness and potential life‐threatening crises. While continuous specialized care is essential, access barriers often delay timely interventions. To address this, we developed MyaLink, a telemedical platform for MG patients.
Maike Stein +13 more
wiley +1 more source
Debater a EuropaEste ensaio percorre sumariamente a história do Estado de Israel e salienta o facto de esta ser marcada por uma constante luta contra vizinhos hostis.
José San‑ Bento
doaj +1 more source
Israel pendiente del informe Winograd [PDF]
, 2007 La constitución de una comisión de investigación para estudiar los errores que se cometieron durante la guerra que Israel libró contra Hezbolá el verano pasado, ha sumergido al país hebreo en una constante tensión política y social.
Amado Castro, Víctor Manuel
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Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Purpose Air pollution has been linked to several neurological conditions, including stroke and neurodegenerative diseases. Evidence regarding its association with multiple sclerosis (MS) remains conflicting, limited by small sample sizes. Methods PubMed, Embase, Scopus, and Cochrane controlled register of trials (CENTRAL) were searched on ...
Ahmad A. Toubasi, Thuraya N. Al‐Sayegh
wiley +1 more source