Results 141 to 150 of about 2,138 (256)

Del estado de derecho liberal moderno al estado constitucional de derecho actual

, 2014
En la presente disertación abordaré el periplo que desarrolla el Estado de Derecho desde la aparición de los Estados modernos hasta la actualidad, mostrando algunas situaciones paradójicas a las que ha dado lugar y analizando las distintas justificaciones que se han realizado en el pensamiento filosófico político y jurídico.
openaire   +1 more source

Favorable outcomes of restrictive treatment indications in chronic lymphocytic leukemia: a retrospective analysis of Brazilian Registry of CLL. [PDF]

Lancet Reg Health Am
de Morais Marques F, Pfister V, Parra F, Perobelli L, Buccheri V, Yamamoto M, Santucci R, Fortier SC, Campos de Molla V, Valerio Ikoma-Colturato MR, Ribeiro G, Hamerschlak N, Costa A, Fogliatto LM, Lucia de Piratininga Figueiredo V, Silveira T, Pitombeira de Lacerda M, Gonçalves MV, Chiattone CS, Brown JR, Arrais-Rodrigues C.   +20 more
europepmc   +1 more source

Kinetoplastid Species Maintained by a Small Mammal Community in the Pantanal Biome. [PDF]

Pathogens, 2022
Santos FM, Sano NY, Liberal SC, Dario MA, Nantes WAG, Alves FM, da Silva AR, De Oliveira CE, Roque ALR, Herrera HM, Jansen AM.   +10 more
europepmc   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Integralism and eugenics: the role of women in Brazilian fascism's national regeneration project. [PDF]

Hist Cienc Saude Manguinhos
Pacheco GS.
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

HIV/AIDS activism and the Unified Health System in Belém, Brazil, 1990-2003. [PDF]

Hist Cienc Saude Manguinhos
Santos PHSD, Paiva CHA.
europepmc   +1 more source

Biological impact of restrictive and liberal fluid strategies at low and high PEEP levels on lung and distal organs in experimental acute respiratory distress syndrome. [PDF]

Front Physiol, 2022
Felix NS, Maia LA, Rocha NN, Rodrigues GC, Medeiros M, da Silva LA, Baldavira CM, Fernezlian SM, Eher EM, Capelozzi VL, Malbrain MLNG, Pelosi P, Rocco PRM, Silva PL.   +13 more
europepmc   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source