Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett +8 more
wiley +1 more source
Eradicating the germs of pauperism: the political economy of the British sanitary movement in the 1830s and 1840s. [PDF]
Hist Cienc Saude ManguinhosBastos DS.
europepmc +1 more source
TBK1‐Associated Primary Lateral Sclerosis Followed by Right Temporal Variant Frontotemporal Dementia
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT We report a 58‐year‐old woman with a novel splice‐site variant in the TANK‐binding kinase 1 (TBK1:c.993–2A>C p.Ala332TyrfsTer39) who sequentially developed primary lateral sclerosis (PLS) followed by right temporal variant frontotemporal dementia (rtvFTD). Neuroimaging demonstrated right anterior temporal atrophy before cognitive symptoms, and
Tomoyasu Matsubara +18 more
wiley +1 more source
Fluid management in sepsis: 5 reasons why less fluid might be more rational. [PDF]
Crit Care SciTaniguchi TM, Taniguchi LU.
europepmc +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Purpose Air pollution has been linked to several neurological conditions, including stroke and neurodegenerative diseases. Evidence regarding its association with multiple sclerosis (MS) remains conflicting, limited by small sample sizes. Methods PubMed, Embase, Scopus, and Cochrane controlled register of trials (CENTRAL) were searched on ...
Ahmad A. Toubasi, Thuraya N. Al‐Sayegh
wiley +1 more source
[The technological escalation of medical practice and the impacts on the physician's relationship with their work]. [PDF]
Salud ColectSchraiber LB.
europepmc +1 more source
La Nación, sujeto y objeto del Estado Liberal Español
Historia Contemporánea, 1998 openaire +3 more sources
OS MOVIMENTOS SOCIAIS NO CONTEXTO DO ESTADO LIBERAL MODERNO
, 2012 O artigo procura caracterizar o contexto sócio-político dentro do qual atuam os movimentos sociais. Parte de uma análise da lógica interna que rege a sociedade liberal moderna no seu todo visando situar as condições de estruturação do espaço do “Político”, as quais condicionam a ação destes movimentos no interior da comunidade moderna.
openaire +1 more source
Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina +11 more
wiley +1 more source
Academic and professional profile and impact of graduates from the Nephrology Graduate Program at UNIFESP. [PDF]
J Bras NefrolFerraz P, Schor N, Kirsztajn GM.
europepmc +1 more source