Results 51 to 60 of about 103,061 (300)
Kalagatos, 2021 O direito de todos a tudo e a vontade de se prejudicarem mutuamente fazem do estado natural um estado de guerra de todos contra todos. Neste estado, nada há de justo. A noção de justiça nasce onde há lei. A lei nasce onde há um poder comum.
Adriano Eurípedes Medeiros Martins
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Infecção natural por Leishmania sp. em flebotomíneos capturados no foco de transmissão de Leishmaniose Tegumentar Americana no município de Piçarras, litoral norte do Estado de Santa Catarina e identificação específica do parasito em amostras clínicas e em cepas isoladas de pacientes. [PDF]
, 2008 TCC(graduação) - Universidade Federal de Santa Catarina. Centro de Ciências Biológicas. Biologia.As Leishmanioses são doenças infecto-parasitárias causadas por protozoários do gênero Leishmania, que acometem cerca de 12 milhões de indivíduos em 88 países
Bittencourt, Ize de Aguiar
core
, 2022 The aim of the current study is to evaluate deforestation in mangaba tree (Hancornia speciosa Gomes) growing areas and environmental valuation in fairs held in Sergipe State, in order to suggest environmental service payment mechanisms to help conserving
Moura, Debora Moreira de Oliveira +2 more
core +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
El Estado estético en Friedrich Schiller. Una analítica de sus alcances y sus posibilidades [PDF]
, 2015 Las cartas sobre la educación estética del hombre (1975) son una de las pocas obras elegidas por Friedrich Schiller para exponer en profundidad sus ideas filosóficas.
Nápoli, Santiago Juan
core
Revista Aurora, 2017 A questão central do presente artigo consistiu em elucidar a relação entre o poder soberano e a manutenção do direito que, por natureza, os homens têm de defender e preservar as suas vidas.
Emmanuel Pedro Ribeiro
doaj +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source