Results 171 to 180 of about 1,021,196 (293)

Prevalence and characterization of human immunodeficiency virus coinfection in patients hospitalized with tuberculosis in a reference hospital in Bogotá [PDF]

Biomedica
Puentes-Ariza GC, Meléndez-Rhenals S, Nocua-Báez LC, Páez-Ardila H.   +3 more
europepmc   +1 more source

Mitochondrial Calcium Uniporter Drives Chemoresistance in Pancreatic Cancer via Glutathione‐Mediated Stemness Maintenance

Advanced Science, EarlyView.
PDAC has a poor prognosis due to chemoresistance. We revealed that MCU upregulation is associated with chemoresistance and stemness in PDAC. MCU‐mediated Ca2+ influx induced ER stress, activating the PERK‐ATF4/NRF2 axis to enhance PSAT1/SLC711 expression and glutathione synthesis, reducing ROS and maintaining stemness.
Zekun Li, Chenyang Meng, Guangcong Shen, Yueying Shan, Junjin Wang, Diliyaer Abudukeremu, Rui Zhao, Bo Ni, Chao Xu, Xiaofan Guo, Jun Yu, Kaiyuan Wang, Shengyu Yang, YunZhan Li, Yongjie Xie, Tianxing Zhou, Jihui Hao, Xiuchao Wang   +17 more
wiley   +1 more source

Draft genome sequence of Exiguobacterium acetylicum GM-14 isolated from beans. [PDF]

BMC Genom Data
Morales-Aguilar JJ, Camacho-Beltrán E, López-Meyer M, Rincón-Enríquez G, Quiñones-Aguilar EE.   +4 more
europepmc   +1 more source

Regulating Tumor Metabolic Reprogramming with Biomimetic Co‐Delivery of Simvastatin and Kynureninase for Immunotherapy

Advanced Science, EarlyView.
After the intravenous injection of biomimetic and pH/ROS‐responsive PTSK@CRM, the nanoparticles can be accumulated in tumors and release Sim and KYNase to inhibit the tumor growth, regulate the metabolism of cholesterol and Kyn, and reverse the immunosuppressive tumor microenvironment.
Jiaxin Yin, Shengcai Yang, Zengguang Liu, Songchen Zhao, Siyu Sun, Ziling Liu, Quanshun Li   +6 more
wiley   +1 more source

Draft genome sequences of <i>Bacillus velezensis</i> and <i>Bacillus subtilis</i> strains with plant growth-promoting and drought resilience potential. [PDF]

Microbiol Resour Announc
Silva Ferreira LV, Gomes de Paula Lana U, Abreu de Oliveira-Paiva C, Aparecida Gomes E, Morais de Sousa Tinoco S.   +4 more
europepmc   +1 more source

Endometrial Assembloid Model Reveals Endometrial Gland Development Regulation by Estradiol‐Driven WNT7B Suppression

Advanced Science, EarlyView.
This study developed a 3D endometrial assembloid model to study how uterine glands form and develop. They discovered key interactions between different cell types and identified WNT7B as a regulator controlled by estradiol‐mediated TGFβ1‐VDR interaction.
Xintong Li, Yanjie Guo, Jianlin Li, Yimeng Li, Leqian Lin, Hoi Kit Matthew Leung, Qingqing Zhang, Kai‐Fai Lee, Ka‐Wang Cheung, Ernest H. Y. Ng, William S. B. Yeung, Philip C. N. Chiu, Cheuk‐Lun Lee   +12 more
wiley   +1 more source

Endogenous pathway dysregulation in Kluyveromyces marxianus under nitrogen limitation drives 2-phenylethyl acetate and 2-phenylethanol overproduction. [PDF]

Sci Rep
González-Lozano KJ, Rutiaga-Quiñones OM, Rodríguez-Flores SN, Contreras-Ramos SM, Rodríguez-Campos J, Aréchiga-Carvajal ET.   +5 more
europepmc   +1 more source

Estado Novo: Corporatism in Contradiction

, 2023
openaire   +2 more sources

Decoding Human Placental Cellular and Molecular Responses to Obesity and Fetal Growth

Advanced Science, EarlyView.
Women with obesity often deliver large‐for‐gestational‐age (LGA) infants. Single‐nucleus RNA sequencing of term placenta reveals that hypoxia and TNF‐α signaling in syncytiotrophoblasts are featured in maternal obesity, but inflammatory signatures in Hofbauer cells and response to lipid or carbohydrate metabolism in fibroblasts are specific to LGA.
Hong Jiang, Emilie Derisoud, Denise Parreira, Nayere Taebnia, Paulo R. Jannig, Reza Zandi Shafagh, Allan Zhao, Congru Li, Macarena Ortiz, Manuel Alejandro Maliqueo, Elisabet Stener‐Victorin, Volker M. Lauschke, Qiaolin Deng   +12 more
wiley   +1 more source

Recrudescence of tuberculosis in the state of São Paulo post-COVID-19: trends and clusters. [PDF]

Rev Saude Publica
Tavares RBV, Zini N, Alves YM, Vinci ALT, Ribeiro NM, Tártaro AF, Caripa VCA, Pelodan MEP, Souza CF, Monroe AA, Ballestero JGA, Pinto IC, Palha PF, Arcêncio RA.   +13 more
europepmc   +1 more source