Results 81 to 90 of about 1,021,999 (290)

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Portaria de Credenciamento ENFAM n. 243 de 10 de setembro de 2015 [PDF]

, 2015
Credencia o curso "52º curso - Ejud-MS - Processo de conhecimento no novo Código de Processo Civil: procedimento comum" promovido pela Escola Judicial do Estado de Mato Grosso do ...
Escola Nacional de Formação e Aperfeiçoamento de Magistrados (Brasil) (ENFAM)
core  

O Novo Estado Neoweberiano

Revista do Serviço Público
O novo Estado Neoweberiano é a iteração contemporânea e atual da Administração Pública Weberiana – praticamente, teoricamente e normativamente. As atualizações de Geert Bouckaert mostram de maneira convincente que tanto o Estado Neoweberiano como a administração pública weberiana original possui os recursos para abordar questões contemporâneas, tanto ...
openaire   +2 more sources

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon, Nathalie Picard, Valeria d'Andrea, Enchi Chang, Joseph Leffler, Eleonora Centofante, Matthew Taylor, Francesca Bardi, Francesca Cavicchiolo, Takao K. Hensch, Stefano Panzeri, Chinfei Chen, Michela Fagiolini   +12 more
wiley   +1 more source

Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz, Josefine Eck, Joel S. Winston, Kate Baker   +3 more
wiley   +1 more source

Emigração e desenvolvimento da previdência social em Portugal Emigration and the development of social welfare in Portugal

Análise Social, 2009
Este artigo analisa a política social do final dos anos 60 e inícios dos anos 70. Demonstra que o alargamento da previdência social corresponde a uma tentativa de ajustamento do governo face à emigração que se iniciou no fim da década de 50.
Victor Pereira
doaj  

Portaria de Credenciamento ENFAM n. 147 de 15 de junho de 2015 [PDF]

, 2015
Credencia o curso "A Decisão Jurídica e sua produção no Novo Código de Processo Civil (Lei n.
Escola Nacional de Formação e Aperfeiçoamento de Magistrados (Brasil) (ENFAM)
core  

Hospital Readmission After Traumatic Brain Injury Hospitalization in Community‐Dwelling Older Adults

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the risk of hospital readmission after an index hospitalization for TBI in older adults. Methods Using data from the Atherosclerosis Risk in Communities (ARIC) study, we used propensity score matching of individuals with an index TBI‐related hospitalization to individuals with (1) non‐TBI hospitalizations (primary analysis)
Rachel Thomas, Connor A. Law, Joan A. Casey, Thomas Mosley, Rebecca F. Gottesman, Ramon Diaz‐Arrastia, Holly Elser, Andrea L. C. Schneider   +7 more
wiley   +1 more source

Are dictatorships more unequal? : economic growth and wage inequality during Portugal's estado novo, 1944-1974. [PDF]

This paper relates the changes in the structure of the Portuguese economy to changes in wage inequality, during 1944-1974, when Portugal had its golden age of growth under a dictatorial regime. We present a new wage data set based on surveys conducted by
Gomes da Silva, Ester, Guilera, Jordi, Lains, Pedro   +2 more
core  

In‐Depth Profiling Highlights the Effect of Efgartigimod on Peripheral Innate and Adaptive Immune Cells in Myasthenia Gravis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin, Liu Dong, Ying Wang, Dingxian He, Chong Yan, Jianying Xi, Haoqin Jiang, Yu Shi, Ming Guan, Chongbo Zhao, Jie Song, Sushan Luo   +11 more
wiley   +1 more source