Results 141 to 150 of about 45,405 (265)

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

open access: yesMolecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad   +35 more
wiley   +1 more source

Predictors of Social Frailty and Depression in Brazilian Patients With Chronic Kidney Disease: A Cross-Sectional Study. [PDF]

open access: yesGeriatr Gerontol Int
Dos Santos DGM   +6 more
europepmc   +1 more source

Gubernamentalización y Estado Social en Colombia

open access: yesReflexión Política, 2005
En este ensayo se pretende analizar la relación entre el proceso de gubernamentalización del Estado colombiano y el sistema de reproducción bipartidista luego de la crisis del modelo liberal clásico. Si bien, entre la I y la II Guerra Mundial se dio en Occidente un replanteamiento de la figura Estado a través del inevitable reconocimiento de la clase ...
openaire   +2 more sources

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

Is the 10-Year Trajectory of Physical Activity Associated With the Incidence of Mild Cognitive Impairment in Older Adults? [PDF]

open access: yesPsychogeriatrics
de Almeida Siqueira Junior J   +5 more
europepmc   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Regionalization and regulation: impact on access to cancer treatment. [PDF]

open access: yesRev Saude Publica
Duarte LS   +6 more
europepmc   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

The Effects of Violent Video Game Characters' Race on Implicit and Explicit Racial Attitudes. [PDF]

open access: yesInt J Psychol
Mariano TE   +4 more
europepmc   +1 more source

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