Results 171 to 180 of about 45,405 (265)

Effectiveness of the Comprehensive-Humanized Care Model in nursing consultation: a case study with older adults. [PDF]

Rev Bras Enferm
Espinoza JBR, Talavera BEM, Medinal DM, Michua MLÁP.   +3 more
europepmc   +1 more source

Del Estado Social al Estado Neoliberal: un nuevo pacto social en Nuestra América

, 2014
Fil: Campana, Melisa. Universidad Nacional de Rosario. Facultad de Cs.politicas y Rel.internacionales. Escuela de Trabajo Social; Argentina.
openaire   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Recrudescence of tuberculosis in the state of São Paulo post-COVID-19: trends and clusters. [PDF]

Rev Saude Publica
Tavares RBV, Zini N, Alves YM, Vinci ALT, Ribeiro NM, Tártaro AF, Caripa VCA, Pelodan MEP, Souza CF, Monroe AA, Ballestero JGA, Pinto IC, Palha PF, Arcêncio RA.   +13 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Social environment and services at the Special Immunobiological Reference Centers: epidemiological study, Minas Gerais, 2022-2024. [PDF]

Epidemiol Serv Saude
Oliveira TM, Araújo ACM, Costa GATD, Gomes LP, Alcantara TMPC, Carvalho NS, Gusmão JD, Levi M, Burian APN, Ferraz ML, Silva TPRD, Matozinhos FP.   +11 more
europepmc   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Land expropriation, litigation, and reinterpretation of space in the genesis of the zoobotanical park of Museu Paraense Emílio Goeldi, 1895-1941. [PDF]

Hist Cienc Saude Manguinhos
Leal D, Sanjad N.
europepmc   +1 more source